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Neurological Disease

Chemical structure

Cat.No.

Product Name

CAS no.

Target

  • YN321980 Neuropeptide Y (22-36) 119019-65-7

    Neuropeptide Y (22-36), a 15 amino acid peptide, is a fragment of Neuropeptide Y.

  • YN483945 Tetanus toxin (830-843) 119260-99-0

    Tetanus toxin (830-843) is a powerful neurotoxin that reaches by retroaxonal transport and transcytosis the cytoplasm ofspinal inhibitory intemeurons and blocks their ability to release neurotransmitters.

  • YN481585 Rocuronium Bromide 119302-91-9

    Rocuronium Bromide is a competitive AchR antagonist, used in modern anaesthesia.

  • YN361015 Cyclic ADP-​ribose 119340-53-3

    Cyclic ADP-ribose (cADPR) is a potent second messenger forcalcium mobilizationthat is synthesized from NAD+by a ADP-ribosyl cyclase. Cyclic ADP-ribose increases cytosolic calcium mainly byRyanodine receptor-mediated relea...

  • YN320592 mAChR-IN-1 119391-56-9

    mAChR-IN-1 is a potent muscarinic cholinergic receptor(mAChR) antagonist with IC50 of 17nM.

  • YN320593 mAChR-IN-1 hydrochloride 119391-73-0

    mAChR-IN-1 hydrochloride is a potentmuscarinic cholinergic receptor (mAChR)antagonist, with an IC50 of 17nM.

  • YN321853 Galanin (1-30), human 119418-04-1

    Galanin (1-30), human is a 30-amino acid neuropeptide, and acts as an agonist ofGalR1 and GalR2 receptors, with Kis of both 1nM.

  • YN360386 Eliprodil 119431-25-3

    Eliprodil(SL-820715) is a non-competitive NR2B-NMDA receptor antagonist(IC50=1 uM), less potent for NR2A- and NR2C-containing receptors(IC50> 100 uM).

  • YN320340 Naloxone benzoylhydrazone 119630-94-3

    Naloxone benzoylhydrazone (NalBzoH) is a mixed agonist/antagonist. Naloxone benzoylhydrazone is a prototypicκ3-opioid receptoragonist, and a partial agonist at the clonedμ and δ opioid receptors, and an antagonist atopioid-like...

  • YN481821 Moguisteine 119637-67-1

    Moguisteine is a novel peripheral non-narcotic antitussive drug.

  • YN380155 Donepezil Hydrochloride 120011-70-3

    Donepezil is a specific and potent AChE inhibitor for bAChE and hAChE with IC50 of 8.12 nM and 11.6 nM , respectively.

  • YN380073 Dihydro Donepezil 120012-04-6

    Dihydro Donepezil (Dihydro E2020) is a metabolite of Donepezil. Donepezil is a specific and potentAChEinhibitor with IC50s of 8.12nM and 11.6nM forbAChE and hAChE, respectively.

  • YN380101 Donepezil 120014-06-4

    Donepezil is a piperidine based, potent, specific, non-competitive and reversible inhibitor of acetylcholinesterase (AChE) used for the treatment of mild to moderate dementia of the Alzheimer's type.

  • YN321895 CRF(6-33)(human) 120066-38-8

    CRF(6-33)(human) is aCRF binding protein (CRF-BP)lig and inhibitor. CRF(6-33)(human) competitively binds theCRF-BPbut not the post-synaptic CRF receptors. CRF(6-33)(human) has anti-obesity effect.

  • YN360837 Fipronil 120068-37-3

    Fipronil is a recalcitrant phenylpyrazole-based pesticide used for flea/tick treatment and termite control that is distributed in urban aquatic environments via stormwater and contributes to stream toxicity.

  • YN1730054 CGS 21680 120225-54-9

    CGS 21680 is a selectiveadenosine A2A receptoragonist, with aKiof 27nM.

  • YN320156 Alvameline 120241-31-8

    Alvameline (Lu25-109) is a partialM1agonist and M2/M3antagonist.

  • YN483970 Protein Kinase C Peptide S... 120253-69-2

    Protein Kinase C Peptide Substrate is targeted to a specific cellular compartment in a manner dependent on second messengers and on specific adapter proteins in response to extracellular signals that activate G-protein-coupled recep...

  • YN360174 Unoprostone 120373-36-6

    Unoprostone, a prostagl and in F2α analogs (PGAs), activatesBK channelsto reduce oxidative stress- and light-induced retinal cell death, and phagocytotic dysfunction. Unoprostone reduces intraocular pressure and is used topic...

  • YN320166 Deramciclane 120444-71-5

    Deramciclane has a high affinity for5-HT2A and 5-HT2Creceptors; it acts as an antagonist at both receptor subtypes and has inverse agonist properties at the 5-HT2Creceptors without direct stimulatory agonist.

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