YN321682 (±)-Vesamicol hydrochloride 120447-62-3

(±)-Vesamicol hydrochloride ((±)-AH5183 hydrochloride) is a potentvesicular acetylcholine transportinhibitor with a Ki of 2nM. (±)-Vesamicol hydrochloride also displays high affinity forσ1 and σ2 receptorswith Kis of 26nM and ...

YN380116 Mofegiline hydrochloride 120635-25-8

Mofegiline hydrochloride (MDL72974A) is a potent and selective enzyme-activated irreversible inhibitor of MAO-B; shows marked selectivity for the B form (IC50 = 680 and 3.6nM for MAO-A and MAO-B).

YN322064 5-HT3 antagonist 3 120635-47-4

5-HT3 antagonist 3 (Compound 15b) is a high-affinity5-HT3 receptorantagonist. 5-HT3 antagonist 3 binds to 5-HT3 receptors in rat brain cortical membranes with Kiof 0.25nM.

YN320325 (RS)-PPG 120667-15-4

(RS)-PPG is a potent and selective agonist for group IIImGluRs. TheEC50s of 5.2μM, 4.7μM, 185μM, and 0.2μM for hmGluR4a, hmGluR6, hmGluR7b, and hmGluR8a, respectively. Anticonvulsive and neuroprotective...

YN380121 (±)-Huperzine A 120786-18-7

(±)-Huperzine A, an active Lycopodium alkaloid extracted from traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (AChE) inhibitor and has been widely used in China for the treatment of Alzheim...

YN1730115 Secretin (33-59), rat 121028-49-7

Secretin (33-59), rat is a 27-aa peptide, acts onsecretin receptor, enhances the secretion of bicarbonate, enzymes, and K+from the pancreas.

YN483786 Melanotan (MT)-II 121062-08-6

Melanotan (MT)-II, a syntheticmelanocortinreceptor agonist, is an injectable peptide hormone used to promote tanning.

YN320248 Amibegron hydrochloride 121524-09-2

Amibegron hydrochloride is a selectiveβ3-adrenoceptoragonist, with an EC50 of 3.5nM forβ-adrenoceptorin rat colon; Amibegron hydrochloride has anxiolytic and antidepressant activity.

YN321237 Pancopride 121650-80-4

Pancopride is a new potent and selective5-HT3receptorantagonist.

YN321421 Naratriptan 121679-13-8

Naratriptan is a selective 5-HT1 receptor subtype agonist and is a triptan drug that is used for the treatment of migraine headaches. Naratriptan is a triptan drug marketed by GlaxoSmithKline and is used for the treatment of mig...

YN360520 (-)-Dizocilpine maleate 121917-57-5

(-)-MK-801 (Dizocilpine) is a potent N-methyl-D-aspartate (NMDA) receptor antagonist with Ki of 30.5 nM.

YN440436 PKA Inhibitor Fragment (6... 121932-06-7

PKA Inhibitor Fragment (6-22) amide is an inhibitor of cAMP-dependentprotein kinase A (PKA), with a Ki of 2.8nM. PKA Inhibitor Fragment (6-22) amide can significantly reverse low-level morphine antinociceptive tolerance i...

YN480876 Magnesium Lithospermate B 122021-74-3

Magnesium Lithospermate B, a derivative of caffeic acid tetramer, and is extracted fromSalviae miltiorrhizae. Magnesium Lithospermate B is widely used for the research of cardiovascular diseases, and it can protect against glucos...

YN360346 Naspm 122306-11-0

Naspm (1-Naphthyl acetyl spermine), a synthetic analogue of Joro spider toxin, is a calcium permeable AMPA (CP-AMPA) receptors antagonist.

YN360615 Rosiglitazone 122320-73-4

Rosiglitazone is a potent antihyperglycemic agent and a potent thiazolidinedione insulin sensitizer with IC50 of 12, 4 and 9 nM for rat, 3T3-L1 and human adipocytes, respectively. Rosiglitazone is a pure ligand of PPAR-gamma, and...

YN321938 Neuropeptide Y (13-36), amid... 122341-40-6

Neuropeptide Y (13-36), amide, human is aneuropeptide Y receptoragonist.

YN270251 Etoposide phosphate disodium 122405-33-8

Etoposide phosphate disodium (BMY-40481 disodium) is a potentanti-cancerchemotherapy agent and a selectivetopoisomerase IIinhibitor to prevent re-ligation of DNA str and s. Etoposide phosphate disodium is the phosphate ester pr...

YN360976 Paederosidic acid methyl este... 122413-01-8

Paederosidic acid methyl ester is a ATP‐sensitiveK+channelactivator, isolated fromP. sc and ens. Paederosidic acid methyl ester exhibits significant central analgesic activity, and enhances the threshold of pain by activating AT...

YN321921 Deltorphin I 122752-15-2

Deltorphin I is aδ-opioid receptoragonist with high affinity and selectivity.

YN321835 Deltorphin 2 122752-16-3

Deltorphin 2 is a selective peptide agonist for theδ opioid receptor.