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Neurological Disease

Chemical structure

Cat.No.

Product Name

CAS no.

Target

  • YN321295 Alosetron 122852-42-0

    Alosetron (GR 68755) is a potent and highly selective serotonin5-HT3 receptorantagonist. Alosetron is used for the research of irritable bowel syndrome (IBS). Alosetron blocks the fast 5HT3-mediated depolarisation of guinea-pi...

  • YN321296 Alosetron ((Z)-2-butenedioat... 122852-43-1

    Alosetron (GR 68755) (Z)-2-butenedioate is a potent and highly selective serotonin5-HT3 receptorantagonist. Alosetron (Z)-2-butenedioate is used for the research of irritable bowel syndrome (IBS). Alosetron (Z)-2-butenedioate...

  • YN321297 Alosetron Hydrochloride 122852-69-1

    Alosetron Hydrochloride is the hydrochloride salt form of alosetron, a potent and selective 5-HT3 receptor antagonist.

  • YN320880 Ziprasidone hydrochloride 122883-93-6

    Ziprasidone HCl is a novel and potent dopamine and serotonin (5-HT) receptor antagonist, used in the treatment of schizophrenia and bipolar disorder.

  • YN380182 Itopride hydrochloride 122892-31-3

    Itopride hydrochloride is an AChE inhibitor. The IC50 of itopride with AChE is 2.04 +/- 0.27 μM.

  • YN360213 XE 991 dihydrochloride 122955-13-9

    XE 991 (LS190926) dihydrochloride is a blocker of Kv7 (KCNQ) channels that potently inhibits KCNQ1 (Kv7.1), KCNQ2 (Kv7.2), KCNQ2 + KCNQ3 (Kv7.3) channel, and M-current with IC50 of 0.75 μM, 0.71 μM, 0.6 μ...

  • YN483949 Prepro VIP (111-122), huma... 123025-94-5

    Prepro VIP (111-122), human is a prepro-vasoactive intestinal polypeptide (VIP)–derived peptide, corresponding to residues 111-122. VIP is present in the peripheral and the central nervous systems where it functions as a nonadr...

  • YN1730007 Dihydrexidine 123039-93-0

    Dihydrexidine (DAR-0100) is a high potent, selective and full efficacyD1-like dopamine receptor (D1/D5)agonist with an IC50 of 10nM for D1 receptor. Dihydrexidine exhibits potent antiparkinsonian activity. Dihydrexidine can s...

  • YN321379 Azasetron hydrochloride 123040-16-4

    Azasetron HCl is a selective 5-HT3 receptor antagonist with IC50 of 0.33 nM used in the management of nausea and vomiting induced by cancer chemotherapy.

  • YN483948 Allatostatin IV 123338-13-6

    Allatostatin IV is an octapeptide. Allatostatins are pleiotropic neuropeptides for inhibition of juvenile hormone synthesis in insects.

  • YN483962 Allatostatin II 123374-34-5

    Allatostatin II is a decapeptid. Allatostatins are pleiotropic neuropeptides for inhibition of juvenile hormone synthesis in insects.

  • YN373178 Phytic acid dodecasodium salt... 123408-98-0

    Phytic acid dodecasodium salt hydrate is a phosphorus storage compound of seeds and cereal grains. Phytic acid dodecasodium salt hydrate is known as a food inhibitor, which has a strong ability to chelate multivalent metal ions, special...

  • YN380119 Rivastigmine 123441-03-2

    Rivastigmine is a cholinesterase inhibitor with IC50 of 5.5 μM. It inhibits acetylcholinesterase (IC50 = 4.15 ?M) and butyrylcholinesterase (IC50 = 37 nM).

  • YN360361 PNU-282987 123464-89-1

    PNU 282987 is a potent agonist of α7-containing neuronal nicotinic acetylcholine receptors with Ki value of 26 nM for the rat receptor.

  • YN322048 Zatosetron maleate 123482-23-5

    Zatosetron maleate is a potent and selective5HT3 receptorantagonist.

  • YN360315 CGP 36742 123690-78-8

    CGP 36742 is a selectiveGABABreceptorantagonist that can penetrate the blood–brain barrier after peripheral administration, with an IC50 of 32 μM. CGP 36742 is useful in treatment of depression.

  • YN360059 (R)-(+)-HA-966 123931-04-4

    (R)-(+)-HA-966 ((+)-HA-966) is a partial agonist/antagonist ofglycine site of the N-methyl-D-aspartate (NMDA)receptor complex. (R)-(+)-HA-966 selectively blocks the activation of the mesolimbic dopamine system by amphetamine. ...

  • YN1730055 CGS 21680 Hydrochloride 124431-80-7

    CGS 21680 HCl is an adenosine A2 receptor agonist with IC50 of 22 nM, exhibits 140-fold over A1 receptor.

  • YN321333 Tolterodine 124937-51-5

    Tolterodine(PNU-200583) is a potent muscarinic receptor antagonists that show selectivity for the urinary bladder over salivary gl and s in vivo.

  • YN321317 Tolterodine tartrate 124937-52-6

    Tolterodine tartrate is a tartrate salt of tolterodine that is a competitive muscarinic receptor antagonist.

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