N-Desmethyltamoxifen hydrochloride
Cat. No. :YN310199
CAS No. :15917-65-4
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order@ubiochem.com| Product Name: | N-Desmethyltamoxifen hydrochloride |
| CAS NO.: | 15917-65-4 |
| Chemical Name: | |
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| Molecular Weight: | 393.95 |
| Molecular Formula: | C₂₅H₂₈ClNO |
| SMILES: | CC/C(C1=CC=CC=C1)=C(C2=CC=C(OCCNC)C=C2)C3=CC=CC=C3.[H]Cl |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | N-Desmethyltamoxifen hydrochloride is the major metabolite of tamoxifen in humans. N-Desmethyltamoxifen, a poor antiestrogen, is a ten-fold more potentprotein kinase C (PKC)inhibitor than Tamoxifen. N-Desmethyltamoxifen hydrochloride is also a potent regulator of ceramide metabolism in human AML cells, limiting ceramide glycosylation, hydrolysis, and sphingosine phosphorylation . |
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