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Rottlerin

Cat. No. :YN310314

  • CAS No. :82-08-6

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    • Products Infomation
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    • Product Name:Rottlerin
      CAS NO.:82-08-6
      Chemical Name:
      Synonyms:Mallotoxin, NSC 56346, NSC 94525
      Molecular Weight:516.54
      Molecular Formula:C₃₀H₂₈O₈
      SMILES:O=C(C1=C2C(C=CC(C)(C)O2)=C(O)C(CC3=C(O)C(C)=C(O)C(C(C)=O)=C3O)=C1O)/C=C/C4=CC=CC=C4
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:Rottlerin, a natural compound purified from Mallotus Philippinensis, is a specific Protein kinase inhibitor with IC50 of 3 μM, 6 μM and 5.3 μM for PKCδ(from baculovirus-infected Sf9 insect cells), PKCδ(from porcine spleen) and CaM kinase III, respectively. Rottlerin also inhibits PKCα, PKCγ, PKCβ, PKCη, CKII and PKA with IC50 of 30 μM, 40 μM, 42 μM, 82 μM, 30 μM and 78 μM, respectively.
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