Rottlerin
Cat. No. :YN310314
CAS No. :82-08-6
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Product Name: | Rottlerin |
CAS NO.: | 82-08-6 |
Chemical Name: | |
Synonyms: | Mallotoxin, NSC 56346, NSC 94525 |
Molecular Weight: | 516.54 |
Molecular Formula: | C₃₀H₂₈O₈ |
SMILES: | O=C(C1=C2C(C=CC(C)(C)O2)=C(O)C(CC3=C(O)C(C)=C(O)C(C(C)=O)=C3O)=C1O)/C=C/C4=CC=CC=C4 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Rottlerin, a natural compound purified from Mallotus Philippinensis, is a specific Protein kinase inhibitor with IC50 of 3 μM, 6 μM and 5.3 μM for PKCδ(from baculovirus-infected Sf9 insect cells), PKCδ(from porcine spleen) and CaM kinase III, respectively. Rottlerin also inhibits PKCα, PKCγ, PKCβ, PKCη, CKII and PKA with IC50 of 30 μM, 40 μM, 42 μM, 82 μM, 30 μM and 78 μM, respectively. |
IC50&Target: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
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References: |
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