Garcinone C
Cat. No. :YN340284
CAS No. :76996-27-5
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order@ubiochem.com| Product Name: | Garcinone C |
| CAS NO.: | 76996-27-5 |
| Chemical Name: | |
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| Molecular Weight: | 414.45 |
| Molecular Formula: | C₂₃H₂₆O₇ |
| SMILES: | CC(C)(O)CCC1=C(O)C(O)=CC(OC2=CC(O)=C(C/C=C(C)/C)C(O)=C23)=C1C3=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Garcinone C, a xanthone derivative, is a natural compound extracted fromGarcinia oblongifolia Champthat is used as an anti-inflammatory, analgesia, astringency and granulation-promoting medicine, and has potential cytotoxic effects on certain cancers. Garcinone C stimulates the expression levels ofATR and 4E-BP1, while efficiently inhibiting the expression levels of cyclin B1, cyclin D1, cyclin E2, cdc2,Stat3 and CDK7. Garcinone C significantly inhibits cell viability of the human Nasopharyngeal carcinoma (NPC) cell lines CNE1, CNE2, HK1 and HONE1 in a time‑ and dose‑dependent manner. |
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