YN320090 5-Carboxamidotryptamine malea... 74885-72-6

5-Carboxamidotryptamine maleate (5-CT maleate) is a potent5-HT1A,5-HT1B,5-HT1D,5-HT5 and 5-HT7receptorsagonist .

YN320241 (Rac)-WAY-161503 75704-24-4

(Rac)-WAY-161503 is a potent, selective, highly affinity5-HT2Creceptoragonist with a Ki of 4nM and an EC50of 12nM. (Rac)-WAY-161503 displays higher affinity for 5-HT2Cthan 5-HT2A and 5-HT2Breceptors. (Rac)-WAY...

YN321015 8-Hydroxy-DPAT hydrobromi... 76135-31-4

8-Hydroxy-DPAT hydrobromide (8-OH-DPAT hydrobromide) is a potent and selective5-HT1Aagonist with apIC50 of 8.19. 8-Hydroxy-DPAT hydrobromide has selectivity of almost 1000 fold for a subtype of the 5-HT1binding site...

YN320218 SR 57227A 77145-61-0

SR 57227A is a potent, orally active and selective5-HT3 receptoragonist, with ability to cross the blood brain barrier. SR 57227A has affinities (IC50) varying between 2.8 and 250nM for 5-HT3 receptor binding sites in rat c...

YN321216 2-Methyl-5-HT 78263-90-8

2-Methyl-5-HT (2-Methyl-5-hydroxytryptamine) is a potent and selective5-HT3receptoragonist. 2-Methyl-5-HT is shown to display anti-depressive-like effects.

YN321218 2-Methyl-5-HT maleate 78263-91-9

2-Methyl-5-HT maleate (2-Methyl-5-hydroxytryptamine maleate) is a potent and selective5-HT3receptoragonist. 2-Methyl-5-HT maleate is shown to display anti-depressive-like effects.

YN320446 8-OH-DPAT 78950-78-4

8-OH-DPAT is a potent and selective5-HTagonist, with apIC50 of 8.19 for 5-HT1A and a Ki of 466nM for 5-HT7; 8-OH-DPAT weakly binds to 5-HT1B (pIC50, 5.42), 5-HT (pIC50<5).

YN320823 Cisapride 81098-60-4

Cisapride is a nonselective 5-HT4 receptor agonist with gastroprokinetic effects.

YN321652 Nefazodone hydrochloride 82752-99-6

an agonist of the vitamin D receptor (VDR) signaling pathway

YN322069 Tertatolol 83688-84-0

Tertatolol is a potent antagonist ofbeta-adrenoceptor and 5-HT receptor, with unique renal vasodilatatory effects.

YN320290 Ketanserin tartrate 83846-83-7

Ketanserin (R41468) tartrate is a selective5-HT2 receptorantagonist. Ketanserin tartrate also blocks hERG current (IhERG) in a concentration-dependent manner (IC50=0.11μM).

YN321455 Mirtazapine 85650-52-8

Mirtazapine is an adrenergic and seroton receptor antagonist, used to treat depression.

YN320426 Asenapine maleate 85650-56-2

Asenapine maleate is a high-affinity antagonist of serotonin, norepinephrine, dopamine and histamine receptors, used for the treatment of schizophrenia and acute mania associated with?bipolar disorder.

YN321269 Setiptiline maleate 85650-57-3

Setiptiline (MO-8282) is aserotonin receptorantagonist. Setiptiline is a tetracyclic antidepressant (TeCA) which acts as a noradrenergic and specific serotonergic antidepressant (NaSSA). Setiptiline acts as a norepinephrine re...

YN320343 Ritanserin 87051-43-2

Ritanserin (R 55667) is a highly potent, relatively selective, orally active, long acting antagonist of5-HT2receptor, with an IC50 of 0.9nM, less active on Histamine H1, Dopamine D2, Adrenergic α1, Adrenergic α2receptors.

YN320360 SCH-23390 maleate 87134-87-0

SCH-23390 maleate (R-(+)-SCH-23390 maleate) is a potent and selectivedopamine D1-like receptorantagonist with Kis of 0.2nM and 0.3nM for theD1 and D5receptor, respectively. SCH-23390 maleate is a potent and high effica...

YN320890 Tandospirone 87760-53-0

T and ospirone (SM-3997) is a potent and selective5-HT1Areceptor partial agonist, with a Ki of 27nM. T and ospirone can be used for the research of the central nervous system disorders and the underlying mechanisms.

YN321382 Tropisetron 89565-68-4

Tropisetron is a 5-HT3 receptor antagonist and α7-nicotinic receptor agonist with an IC50 of 70.1 ± 0.9 nM for 5-HT3 receptor.

YN320895 Xaliproden hydrochloride 90494-79-4

Xaliproden hydrochloride (SR57746A) is a potent, selective and orally active agonist of5-HT1Areceptor, shows a high affinity for 5-HT1Aspecific binding sites in the rat hippocampus (IC50=3nM). Xaliproden hydrochloride is als...

YN321238 Ipsapirone 95847-70-4

Ipsapirone (TVX Q 7821) is an anxiolytic compound and a5-HT1Areceptor partial agonist. Ipsapirone (TVX Q 7821) also exhibits5-HT1Areceptor antagonistic effect, and only at high doses it can also produce an inhibitory eff...