YN321229 SCH-23390 hydrochloride 125941-87-9

SCH-23390 hydrochloride (R-(+)-SCH-23390 hydrochloride) is a potent and selectivedopamine D1-like receptorantagonist with Kis of 0.2nM and 0.3nM for theD1 and D5receptor, respectively. SCH-23390 hydrochloride is a potent...

YN320232 Fananserin 127625-29-0

Fananserin (RP 62203) is an orally bioavailable, potent and selective5-hydroxytryptamine2 (5-HT2)receptor antagonist, with a Ki of 0.37nM for the rat 5-HT2Areceptor. Fananserin also is a selectivedopamine D4receptor antagonist...

YN322088 5-HT3 antagonist 2 128199-93-9

5-HT3 antagonist 2 is a5-HT3receptor antagonist.

YN320101 Ocaperidone 129029-23-8

Ocaperidone is an effective antipsychotic agent, acting as a potent5-HT2 and dopamine D2antagonist, and a5-HT1Aagonist, with Kis of 0.14nM, 0.46nM, 0.75nM, 1.6nM and 5.4nM for 5-HT2, a1-adrenergic receptor, dopamine D2, ...

YN321567 Perospirone hydrochloride 129273-38-7

Perospirone is an atypical or second-generation antipsychotic of the azapirone family that antagonizes serotonin 5HT2A receptors and dopamine D2 receptors. It also displays affinity towards 5HT1A receptors as a partial agonist.

YN322076 5-HT3 antagonist 1 129294-09-3

5-HT3 antagonist 1 is a potent and selective antagonist ofserotonin 3 (5-HT3) receptor.

YN320168 (±)-Fabesetron hydrochloride 129299-81-6

(±)-Fabesetron hydrochloride ((±)-FK1052) is the racemate of Fabesetron hydrochloride, which is a potent5-HT3 and 5-HT4receptor dual antagonist.

YN320281 Fabesetron 129300-27-2

Fabesetron (FK1052) is an orally active5-HT3receptorantagonist with5-HT4receptorantagonistic activity. Fabesetron (FK1052) can be used in the study for both acute and delayed emesis induced by cancer chemotherapy.

YN320883 Aripiprazole 129722-12-9

Aripiprazole is a novel atypical antipsychotic drug that is reported to be a high-affinity 5-HT receptor partial agonist.

YN320070 Dehydroaripiprazole 129722-25-4

Dehydroaripiprazole (OPC-14857) is an active metabolite of Aripiprazole. Aripiprazole is an antipsychotic agent and is metabolized by CYP3A4 and CYP2D6 forming mainly Dehydroaripiprazole. Dehydroaripiprazole has with ant...

YN320344 Eplivanserin 130579-75-8

Eplivanserin is a potent, selective and orally available5-HT2receptorantagonist, with an IC50 of 5.8nM in rat cortical membrane, and aKdof 1.14nM.

YN320345 Eplivanserin (mixture) 130581-13-4

Eplivanserin mixture (SR-46349 mixture) is a selectiveserotonin reuptakeinhibitor and a5-HT2Areceptorantagonist, extracted from patent WO 2005/002578 A1.

YN320164 5-HT6/7 antagonist 1 131999-28-5

5-HT6/7 antagonist 1 is a multifunctional lig and that antagonizes5-HT6/7/2A and D2receptors, without interacting with M1 receptors and hERG channels.

YN321294 Alosetron (Hydrochloride(1:X... 132414-02-9

Alosetron (GR 68755) Hydrochloride(1:X) is a potent and highly selective serotonin5-HT3 receptorantagonist. Alosetron Hydrochloride(1:X) is used for the research of irritable bowel syndrome (IBS). Alosetron Hydrochloride(1:...

YN320160 Lesopitron dihydrochloride 132449-89-9

Lesopitron dihydrochloride is a full and selective5-HT1Areceptor agonist with IC50 of 125nM in rat hippocampal membranes.

YN320877 Olanzapine 132539-06-1

Olanzapine is a high affinity for 5-HT2 serotonin and D2 dopamine receptor antagonist.

YN320759 Blonanserin 132810-10-7

Blonanserin (AD-5423) is a potent  and orally active5-HT2A(Ki=0.812nM) and dopamine D2 receptor(Ki=0.142 nM) antagonist. Blonanserin is usually acts as an atypical antipsychotic agent and can be used for the research of...

YN320514 Org-12962 132834-56-1

Org-12962 is a potent, selective and orally active5-HT2Creceptoragonist with apEC50value of 7.01. Org-12962 also exhibits high effacy for the 5-HT2A and 5-HT2Breceptor withpEC50s of 6.38 and 6.28, respectively.Org-12962...

YN321544 Ramosetron Hydrochloride 132907-72-3

Ramosetron Hydrochloride is the hydrochloride salt of ramosetron, a selective serotonin (5-HT) receptor antagonist with potential antiemetic activity.

YN321206 EMD 56551 133109-86-1

EMD 56551 is a potent and selective5-HT1A receptoragonist. EMD 56551 exerts anxiolytic activity.