YN321374 Quetiapine D4 fumarate 1287376-15-1

Quetiapine D4 fumarate is the deuterium labeled Quetiapine fumarate. Quetiapine fumarate is a 5-HT receptors agonist and a dopamine receptor antagonist. Antidepressant and anxiolytic effects.

YN321133 Iloperidone hydrochloride 1299470-39-5

Iloperidone hydrochloride (HP 873 hydrochloride) is aD2/5-HT2receptor antagonist. Iloperidone hydrochloride is an atypical antipsychotic for the schizophrenia symptoms.

YN320765 SEP-363856 hydrochloride 1310422-41-3

SEP-363856 hydrochloride（SEP-856 hydrochloride）, an orally active and CNS active psychotropic agent with a unique, non-D2/5-HT2A mechanism of action, exerts its antipsychotic-like effects. SEP-363856 hydrochloride（SEP...

YN321177 PF-04995274 1331782-27-4

PF-04995274 (PF-4995274) is a potent, high-affinity, orally active and partial agonist of serotonin 4 receptor (5-HT4R) with EC50 of 0.47 nM, 0.36 nM, 0.37 nM and 0.26 nM for human 5-HT4A/4B/4D/4E, respectively. A...

YN320078 YL0919 1339058-04-6

YL0919 is an orally active antidepressant agent with dual activity as a highly seletive 5-HT uptakeblocker and an effective 5-HT1A receptoragonist (Ki=0.19nM). YL0919 inhibits the uptake of [3H]-5-HT into rat cerebral cortic...

YN320622 (R)-Praziquantel D11 1399880-38-6

(R)-Praziquantel D11 is the deuterium labeled (R)-Praziquantel. (R)-Praziquantel, the active enantiomer of Praziquantel, is a partial agonist of the human 5-HT2B receptor. (R)-Praziquantel acts as an antischistosomal eutomer.

YN321067 Asenapine hydrochloride 1412458-61-7

Asenapine hydrochloride, an antipsychotic, is a5-HT(1A, 1B, 2A, 2B, 2C, 5A, 6, 7) and Dopamine (D2, D3, D4)receptor antagonist with Ki values of 0.03-4.0nM for 5-HT and 1.3, 0.42, 1.1nM for Dopamine receptor, respecti...

YN321097 TG6-10-1 1415716-58-3

TG6-10-1 is anEP2antagonist, shows low-nanomolar antagonist activity against only EP2, >300-fold selectivity over human EP3, EP4, and IP receptors, 100-fold selectivity over EP1 receptors.

YN320400 Opiranserin 1441000-45-8

Opiranserin, a non-opioid and non-NSAID analgesic c and idate, is a dual antagonist ofglycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A), with IC50s of 0.86 and 1.3μM, respectively. Opiranserin shows a...

YN320235 SB 243213 dihydrochloride 1780372-25-9

SB 243213 dihydrochloride is an orally active, selective and high-affinity5-HT2Creceptorantagonist with a pKi of 9.37 and apKbof 9.8 for human 5-HT2Creceptor. SB 243213 dihydrochloride shows greater than a 100-fold selectivi...

YN320403 Masupirdine mesylate 1791396-46-7

Masupirdine mesylate (SUVN-502 mesylate) is a potent, selective, orally bioavailable, and brain penetrant5-HT6 receptorantagonist (Kiof 2.04nM for human 5-HT6 receptor). Masupirdine mesylate (SUVN-502 mesylate) shows high ...

YN321350 Flibanserin D4 2122830-90-2

Flibanserin D4 is a deuterium labeled Flibanserin (BIMT-17). Flibanserin is a full agonist of the serotonin 5-HT1A receptor (Ki=1nM) and an antagonist of 5-HT2A (49nM).

YN320980 Vortioxetine D8 2140316-62-5

Vortioxetine D8 is a deuterium labeled Vortioxetine. Vortioxetine is an inhibitor of5-HT1A, 5-HT1B, 5-HT3A, 5-HT7receptor and SERT, with Ki values of 15nM, 33nM, 3.7nM, 19nM and 1.6nM, respectively .

YN321729 Harmine

Harmine is an alkaloid of the β-carboline family that regulates PPARγ expression through inhibition of the Wnt signaling pathway. It also selectively binds to MAO-A and reversibly inhibits monoamine oxidase A (MAO-A) but n...