YN321610 Pimethixene maleate 13187-06-9

Pimethixene (Pimetixene) maleate, an antihistamine, anntimigraine agent and antiserotonergic compound, is a highly potent antagonist of a broad range of monoamine receptors, including a variety of serotonin receptors. Pimet...

YN321594 Pindolol 13523-86-9

Pindolol (LB-46) is a nonselective β-blocker with partial beta-adrenergic receptor agonist activity, also functions as a 5-HT1A receptor weak partial antagonist (Ki=33nM).

YN321662 Alprenolol 13655-52-2

Alprenolol is a non-selective beta blocker as well as 5-HT1A receptor antagonist. The reference for administration is 10 mg/kg.

YN321663 Alprenolol hydrochloride 13707-88-5

Alprenolol hydrochloride is the hydrochloride salt form of alprenolol, which is an beta adrenergic receptorantagonist and is used as an antihypertensive, anti-anginal, and anti-arrhythmic agent.

YN321391 Pizotifen 15574-96-6

Pizotifen (Pizotyline, BC-105) is a potent antagonist of 5-Hydroxytryptamine (5-HT, Serotonin) 5-HT2 receptor with a high affinity for 5-HT1C binding site.

YN321263 BGC20-761 17375-63-2

BGC20-761 is a selecvtive5-HT6 and dopamine receptorantagonist (human receptorKivalues: 5-HT6 (20nM), 5-HT2A (69nM), D2 (140nM). BGC20-761, can enhance long-term memory. BGC20-761 has potential utility as an antipsychot...

YN321600 Metergoline 17692-51-2

Metergoline is a psychoactive drug of the ergoline chemical class which acts as a lig and for various serotonin and dopamine receptors.

YN321514 Trazodone hydrochloride 25332-39-2

Trazodone HCl is an antidepressant belonging to the class of serotonin receptor antagonists and reuptake inhibitors for treatment of anxiety disorders.

YN321128 Loxapine succinate 27833-64-3

Loxapine Succinate is a D2DR and D4DR inhibitor, serotonergic receptor antagonist and also a dibenzoxazepine anti-psychotic agent.

YN321316 Tianeptine sodium salt 30123-17-2

Tianeptine sodium is a selective serotonin reuptake enhancer (SSRE), used for treating major depressive episodes.

YN320717 Flumexadol 30914-89-7

Flumexadol is an orally active non-narcotic analgesic. Flumexadol is a selective and affinity5-HT2Creceptoragonist with a Ki of 25nM for the (+)-enantiomer of Flumexadol, and is 40-fold selective over the 5-HT2Areceptor.

YN321742 Gamma-Mangostin 31271-07-5

Gamma-Mangostin is a novel competitive5-hydroxytryptamine 2A (5-HT2A) receptorsantagonist, purified from the fruit hull of the medicinal plantGarcinia mangostana. Gamma-Mangostin is a inhibitor ofTransthyretin (TTR) fibrillizat...

YN320606 Peptide 401 32908-73-9

Peptide 401, a potent mast cell degranulating factor from bee venom, suppresses the increased vascular permeability due to intradermal injection of various smooth muscle spasmogens (histamine, and 5-HT).

YN321614 Buspirone hydrochloride 33386-08-2

Buspirone is a serotonergic (5HT(1A) receptor agonist) anxiolytic drug with some D(2) dopaminergic effect, used for anxiety disorders.

YN321562 Urapidil 34661-75-1

Urapidil is an antihypertensive drug acting as an α1 adrenoreceptor antagonist and a 5-HT1A agonist.

YN321320 Talipexole dihydrochloride 36085-73-1

Talipexole dihydrochloride (B-HT 920 dihydrochloride) is a dopamine D2 receptor agonist, α2-adrenoceptor agonist and 5-HT3 receptor antagonist, which displays antiParkinsonian activity.

YN321665 Bemesetron 40796-97-2

Bemesetron (MDL 72222) is a selective5-HT3receptorantagonist with an IC50 of 0.33nM. Neuroprotective effect.

YN321621 Cyproheptadine hydrochloride ... 41354-29-4

Cyproheptadine hydrochloride is non-selective 5HT2 antagonist with IC50 of 0.6 nM. Also a SETD7/9 inhibitor.

YN321689 Clocapramine 47739-98-0

Clocapramine is an antagonist of theD2,5-HT2Areceptors.

YN321734 Isocorynoxeine 51014-29-0

Isocorynoxeine, an isorhynchophylline-related alkaloid, exhibits a dose-dependent inhibition of 5-HT2A receptor-mediated current response with an IC50 of 72.4 μM.