YN321034 Brexpiprazole 913611-97-9

Brexpiprazole (OPC-34712), an atypical antipsychotic drug, is a partial agonist of human5-HT1A and dopamine receptor with Kis of 0.12nM and 0.3nM, respectively. Brexpiprazole is also a5-HT2Areceptor antagonist with a Ki of ...

YN322023 Ansofaxine hydrochloride 916918-84-8

Ansofaxine hydrochloride (LY03005; LPM570065) is a triple reuptake inhibitor; inhibitsserotonin,dopamine and norepinephrinereuptake with IC50 values of 723, 491 and 763nM, respectively.

YN320282 Piromelatine 946846-83-9

Piromelatine (Neu-P11) is amelatonin MT1/MT2receptor agonist,serotonin 5-HT1A/5-HT1Dagonist, and serotonin 5-HT2Bantagonist. Piromelatine (Neu-P11) possesses sleep promoting, analgesic, anti-neurodegenerative, anxiolytic...

YN320979 Vortioxetine hydrobromide 960203-27-4

Vortioxetine hydrobromide is a multimodal serotonergic agent, inhibits5-HT1A, 5-HT1B, 5-HT3A, 5-HT7receptor and SERTwith Ki values of 15nM, 33nM, 3.7nM, 19nM and 1.6nM, respectively.

YN320242 AS19 1000578-26-6

AS19 is a potent, selective5-HT7receptoragonist with an IC50 value of 0.83nM and a Ki of 0.6nM. AS19 is selective for5-HT7over 5-HT1A, 5-HT1B, 5-HT1D, and 5-HT5Areceptors (Kis = 89.7nM, 490nM, 6.6nM and 98...

YN320733 SB 242084 hydrochloride 1049747-87-6

SB 242084 hydrochloride is a 5-HT2C receptor antagonist(pKi=9.0) that displays 158- and 100-fold selectivity over 5-HT2A and 5-HT2B receptors respectively.

YN320439 LP-211 1052147-86-0

LP-211 is a selective and blood−brain barrier penetrant5-HT7receptoragonist, with a Ki of 0.58nM, with high selectivity over 5-HT1Areceptor (Ki, 188nM) and D2receptor (Ki, 142nM).

YN320907 Cariprazine hydrochloride 1083076-69-0

Cariprazine, a novel second-generation antipsychotic, is a D3-preferring dopamine D2/D3 receptor partial agonist.

YN320265 WAY-100635 Maleate 1092679-51-0

WAY-100635 Maleate is a potent and selective 5-HT receptor antagonist with IC50 of 0.95 nM.

YN320694 Ziprasidone amino acid 1159977-64-6

Ziprasidone amino acid (Ziprasidone Impurity C) is an impurity of Ziprasidone. Ziprasidone is a combined5-HT (serotonin) and dopamine receptorantagonist. Ziprasidone exhibits potent effects of antipsychotic activity.

YN321109 Agomelatine hydrochloride 1176316-99-6

Agomelatine hydrochloride (S-20098 hydrochloride) is a specific agonist ofMT1 and MT2receptors with Kis of 0.1, 0.06, 0.12, and 0.27nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and HEK-hMT2, respectively. Agomelatin...

YN321242 Lumateperone tosylate 1187020-80-9

Lumateperone tosylate (ITI-007 tosylate) is a 5-HT2A receptor antagonist (Ki = 0.54nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors (Ki = 32nM), and a SERT blocker (Ki =...

YN321423 Naratriptan D3 Hydrochlorid... 1190021-64-7

Naratriptan D3 Hydrochloride is the deuterium labeled Naratriptan, which is a selective 5-HT1 receptor subtype agonist.

YN320724 Brexpiprazole S-oxide 1191900-51-2

Brexpiprazole S-oxide (DM-3411) is a main metabolite of Brexpiprazole and is metabolized by cytochrome P450 3A4 (CYP3A4). Brexpiprazole is an atypical antipsychotic agent and a partial agonist of human5-HT1A and dopamine ...

YN321004 CP-809101 hydrochloride 1215721-40-6

CP-809101 hydrochloride is a potent and selective 5-HT2C receptor agonist with pEC50 of 9.96/7.19/6.81 for human 5-HT2C/5-HT2B/5-HT2A receptors respectively.

YN321458 Mirtazapine D3 1216678-68-0

Mirtazapine D3 (Org3770 D3; 6-Azamianserin D3) is a deuterium labeled Mirtazapine. Mirtazapine is a5-HT receptorinhibitor. Mirtazapine is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaS...

YN321375 Quetiapine D4 hemifumarate 1217310-65-0

Quetiapine D4 hemifumarate is the deuterium labeled Quetiapine hemifumarate. Quetiapine hemifumarate is a 5-HT receptors agonist and a dopamine receptor antagonist. Antidepressant and anxiolytic effects.

YN320804 LY 344864 hydrochloride 1217756-94-9

LY 344864 hydrochloride is a selective5-HT1Fagonist with a Ki of 6nM.

YN321486 Chlorpromazine D6 hydrochlor... 1228182-46-4

Chlorpromazine D6 hydrochloride is the deuterium labeled Chlorpromazine. Chlorpromazine is an inhibitor of dopamine receptor, 5-HT receptor, potassium channel, sodium channel.

YN320402 Brilaroxazine 1239729-06-6

Brilaroxazine (RP5603) is a potent and orally active multimodaldopamine (DA)/serotonin (5-HT)modulator. Brilaroxazine is a partial agonist of dopamine (DA) D2, D3, and D4 receptors, 5-HT1A (Ki=1.5nM)  and 5-HT2A ...