Ensartinib hydrochloride
Cat. No. :YN440087
CAS No. :2137030-98-7
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order@ubiochem.com| Product Name: | Ensartinib hydrochloride |
| CAS NO.: | 2137030-98-7 |
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| Molecular Weight: | 634.36 |
| Molecular Formula: | C₂₆H₂₉Cl₄FN₆O₃ |
| SMILES: | O=C(C1=NN=C(N)C(O[C@@H](C2=C(Cl)C=CC(F)=C2Cl)C)=C1)NC3=CC=C(C(N4C[C@@H](C)N[C@@H](C)C4)=O)C=C3.[2HCl] |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Ensartinib (X-396) is a potent new-generation ALK inhibitor with high activity against a broad range of known crizotinib-resistant ALK mutations and CNS metastases. It potently inhibits both wild-type ALK and ALK variants (F1174, C1156Y, L1196M, S1206R, T1151, and G1202R mutants) with in vitro IC50s of <4 nM. |
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