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A 83-01

Cat. No. :YN440094

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    • Products Infomation
    • Biological Activity
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    • Product Name:A 83-01
      CAS NO.:909910-43-6
      Chemical Name:
      Synonyms:
      Molecular Weight:421.52
      Molecular Formula:C₂₅H₁₉N₅S
      SMILES:S=C(N1N=C(C2=NC(C)=CC=C2)C(C3=CC=NC4=CC=CC=C34)=C1)NC5=CC=CC=C5
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:A 83-01 is a potent inhibitor of TGF-β type I receptorALK5 kinase, type I nodal receptorALK4 and type I nodal receptorALK7, with IC50s of 12nM, 45nM and 7.5nM against the transcription induced byALK5,ALK4 and ALK7, respectively.
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