CEP-37440
Cat. No. :YN440350
CAS No. :1391712-60-9
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order@ubiochem.com| Product Name: | CEP-37440 |
| CAS NO.: | 1391712-60-9 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 580.12 |
| Molecular Formula: | C₃₀H₃₈ClN₇O₃ |
| SMILES: | O=C(NC)C1=CC=CC=C1NC2=NC(NC3=CC=C4C(CCC[C@H](N5CCN(CCO)CC5)C4)=C3OC)=NC=C2Cl |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | CEP-37440 is a novel potent and selective Dual FAK/ALK inhibitor with IC50 s of 2.3nM (FAK) and 120nM(ALK cellular IC50 in 75% human plasma). Preparation of fused bicyclic 2,4-diaminopyrimidine derivatives as a dual ALK and FAK inhibitor By Jacobs, Martin J.; Ott, Gregory R. From PCT Int. Appl. (2013), WO 2013134353 A1 20130912. |
| IC50&Target: | |
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