TGFβRI-IN-2
Cat. No. :YN440218
CAS No. :1976038-41-1
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order@ubiochem.com| Product Name: | TGFβRI-IN-2 |
| CAS NO.: | 1976038-41-1 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 411.82 |
| Molecular Formula: | C₂₀H₁₅ClFN₅O₂ |
| SMILES: | O=C(N)CN(C1=C2C=CN=C1)C(N2C3=CC(C4=CC(Cl)=CC=C4F)=NC=C3C)=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | TGFβRI-IN-2 (compound 18) is a potent, selective and orally active(Activin-Like Kinase 5) ALK 5inhibitor withpIC50 and pEC50values of 7.6 and 6.63, respectively. TGFβRI-IN-2 can produce observed cardiac toxicity in vivo at high dose. |
| IC50&Target: | |
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| In Vivo: | |
| Clinical Trial: | |
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