YN270530 Euphorbia Factor L1 76376-43-7

Euphorbia factor L1 can enhance the ATP hydrolysis activity of ABCB1 stimulated by verapamil. Euphorbia factor L1 inhibits the efflux of ABCB1 in KBv200 and MCF-7/adr cells, does not downregulate their expression ei...

YN372472 Lisinopril 76547-98-3

Lisinopril (MK-521) is angiotensin-converting enzyme inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks.

YN410126 Danshensu 76822-21-4

Danshensu, a herbal preparation used in traditional Chinese medicine, possesses potential antitumor and anti?angiogenesis effects.

YN370202 Ro-15-2041 77448-87-4

Ro 15-2041 is a selective plateletphosphodiesteraseinhibitor with antithrombotic properties.

YN372758 Pimobendan hydrochloride 77469-98-8

Pimobendan hydrochloride (UD-CG115 hydrochloride) is a selective inhibitor of PDE3 with IC50 of 0.32μM.

YN372932 Enoximone 77671-31-9

Enoximone is an inotropic vasodilating agent and a selective and orally activephosphodiesterase III (PDE3)inhibitor with an IC50 of 5.9μM. Enoximone induces vasodilatation and increases intracellular levels of cAMP by i...

YN320179 Ecastolol 77695-52-4

Ecastolol is abeta adrenergic receptorantagonist, with antianginal activities.

YN321387 Doxazosin mesylate 77883-43-3

Doxazosin, a quinazoline-derivative, selectively antagonizes postsynaptic α1-adrenergic receptors, used in the treatment of high blood pressure and urinary retention associated with benign prostatic hyperplasia.

YN480144 Droxicainide 78289-26-6

Droxicainide is an antiarrhythmic agent.

YN480028 FKK 78299-79-3

FKK is an indazole derivative and also a novel bronchodilator.

YN370115 MY-5445 78351-75-4

MY-5445 is a specific phosphodiesterase type 5 (PDE5) inhibitor. MY-5445 selectively inhibitsc GMP PDE with a Ki of 1.3μM.

YN372186 Milrinone 78415-72-2

Milrinone is a phosphodiesterase 3 (PDE3) inhibitor, used to increase the heart's contractility.

YN360994 Praeruptorin E 78478-28-1

Praeruptorin C and E can relax swine coronary artery and decrease contractility in guinea-pig left atria, these effects are similar in many respects to those displayed by drugs that have calcium entry blocking activity. Praeruptorin D ...

YN370053 BML-111 78606-80-1

BML-111, a lipoxin A4analog, is alipoxin A4receptoragonist. BML-111 represses the activity of angiotensin converting enzyme (ACE) and increases the activity of angiotensinconverting enzyme 2 (ACE2). BML-111 has antiangioge...

YN321495 Ozagrel hydrochloride 78712-43-3

Ozagrel HCl is a selective thromboxane A(2) (TXA(2)) synthetase inhibitor with IC50 of 11 nM for rabbit platelet, used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral ischaemia.

YN360989 Guanfu base G 78969-72-9

Guanfu base G is an antiarrhythmic alkaloid isolated fromAconitum coreanum. Guanfu base G inhibitsHERGchannel current with an IC50 of 17.9μM.

YN320542 Daltroban 79094-20-5

Daltroban (BM-13505) is a selective and specificthromboxane A2 (TXA2) receptorantagonist. Daltroban increase intracellular calcium in vascular smooth muscle cells. Daltroban shows protective effect in reperfusion injury.

YN483580 Latinone 79157-36-1

Latinone, a neoflavonoid isolated from Dalbergia cochinchinensis, has antiosteoporotic activity.

YN484180 Mioflazine 79467-23-5

Mioflazine is an orally activenucleoside transportinhibitor, has the potential for sleep disorders treatment. Mioflazine inhibits nucleoside uptake.

YN321122 Octreotide acetate 79517-01-4

Octreotide Acetate is the acetate salt of a cyclic octapeptide. It is a long-acting octapeptide with pharmacologic properties mimicking those of the natural hormone somatostatin.