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Cardiovascular Disease

Chemical structure

Cat.No.

Product Name

CAS no.

Target

  • YN330315 20-HETE 79551-86-3

    20-HETE (20-hydroxy Arachidonic Acid) is a CYP450 metabolite and a potent vasoconstrictor. 20-HETE is an endogenous inhibitor of the large-conductanceCa2+-activated K+channelin renal arterioles. 20-HETE constricts smoot...

  • YN370227 Acetylhydrolase-IN-1 79637-91-5

    Acetylhydrolase-IN-1 is a 1-Alkyl-2-acetylglycerophosphocholine esterase (Alkylacetyl-GPC: acetylhydrolase) inhibtor.

  • YN361063 Dopropidil 79700-61-1

    Dopropidil is a novel anti-anginal calcium ion modulating agent, possessing intracellular calcium antagonist activity and anti-ischemic effects in several predictive animal models.

  • YN320189 Ko-3290 79848-61-6

    Ko-3290 is an antagonist ofβ-adrenoceptor, with cardioselectivity and antilipolytic effects in animals.

  • YN371593 2'-Ethyl Simvastatin 79902-42-4

    2'-Ethyl Simvastatin (compound 6) is a Mevinolin analog, withHMG-CoA reductaseinhibition.

  • YN372446 Simvastatin 79902-63-9

    Simvastatin is a competitive inhibitor of HMG-CoA reductase with Ki of 0.1-0.2 nM in cell-free assays.

  • YN372756 Nafamostat hydrochloride 80251-32-7

    Nafamostat hydrochloride, a synthetic serine protease inhibitor, is an anticoagulant. Nafamostat hydrochloride supresses T cell auto-reactivity by decreasing granzyme activity and CTL cytolysis. Nafamostat hydrochloride blocks acti...

  • YN373131 Gypenoside XVII 80321-69-3

    Gypenoside XVII, a novel phytoestrogen belonging to the gypenosides, can activateestrogen receptors.

  • YN483417 Gypenoside XIII 80325-22-0

    Gypenoside XIII is belonging to the gypenosides. Gypenosides, extracted fromGynostemma pentaphyllum, have various pharmacological properties and protect against cardiovascular diseases, especially atherosclerosis.

  • YN410113 Sanggenon C 80651-76-9

    Sanggenon C is a flavanone Diels-Alder adduct compound, which is isolated from the root bark ofMorus cathayana. Sanggenon C exerts protective effects against cardiac hypertrophy and fibrosis via suppression of thecalcineurin/NFA...

  • YN482738 Fuziline 80665-72-1

    Fuziline is a alkaloid isolated from the lateral roots ofAconitum carmichaelii.

  • YN370336 Rentiapril 80830-42-8

    Rentiapril is an orally activeangiotensin converting enzyme (ACE)inhibitor with antihypertensive activity.

  • YN373970 Pivalopril 81045-50-3

    Pivalopril is a new orally active angiotensin converting enzyme (ACE) inhibitor.

  • YN372750 Pravastatin 81093-37-0

    Pravastatin is a lipoprotein-lowering drug via reversibly inhibiting hydroxymethylglutaryl-CoA (HMG-CoA) reductase and the synthesis of very-low-density lipoproteins.

  • YN371739 3α-Hydroxy pravastatin sodiu... 81093-43-8

    3α-Hydroxy pravastatin sodium is the major metabolite of Pravastatin. Pravastatin is a competitive HMG-CoA reductase inhibitor.

  • YN372751 Pravastatin sodium 81131-70-6

    Pravastatin sodium is an HMG-CoA reductase inhibitor against sterol synthesis with IC50 of 5.6 μM.

  • YN321651 Esmolol hydrochloride 81161-17-3

    Esmolol is a cardioselective b-blocker, used to control rapid heartbeats or abnormal heart rhythms.

  • YN410143 (S)-Falcarinol 81203-57-8

    (S)-Falcarinol ((S)-Panaxynol), one of the major polyacetylenes isolated fromPanax ginseng, has antitumor activity. (S)-Falcarinol is the most potent antiplatelet agent in ginseng and its mechanism of action is chiefly due to the i...

  • YN370193 Modecainide 81329-71-7

    Modecainide is a major metabolite of Encainide, which is an antiarrhythmic agent.

  • YN480020 RP 54275 81364-78-5

    RP 54275 (2-Octadecyl-1H-indole-5-carboxylic acid) is a novel hypocholesterolaemic drug.

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