YN370884 Simvastatin acid ammonium 139893-43-9

Simvastatin ammonium is an active metabolite of simvastatin lactone mediated by CYP3A4/5 in the intestinal wall and liver (pKa=5.5). Simvastatin ammonium reduces indoxyl sulfate-mediated reactive oxygen species and modulates OA...

YN321979 C-Type Natriuretic Peptide... 141294-77-1

C-Type Natriuretic Peptide (1-53), human is the 1-53 fragment of C-Type Natriuretic Peptide. C-Type Natriuretic Peptide is natriuretic peptide family peptide that is involved in the maintenance of electrolyte-fluid balance and ...

YN320182 LCB-2853 141335-10-6

LCB-2853 is an antagonist ofthromboxane A2 (TXA2) receptor, with antiplatelet and antithrombotic activities.

YN372787 Argatroban monohydrate 141396-28-3

Argatroban is a direct, selective thrombin inhibitor with anticoagulant effects.

YN360484 Levosimendan 141505-33-1

Levosimendan is a calcium sensitizer acting through calcium-dependent binding to cardiac troponin C (cTnC), provides treatment for heart failure.

YN360716 Dronedarone Hydrochloride 141625-93-6

Dronedarone HCl is a multichannel blocker targeting potassium channel, sodium channel and calcium channel, used as an antiarrhythmic drug for treatment of atrial fibrillation (AF).

YN321327 Dronedarone 141626-36-0

Dronedarone is a derivative of amiodarone which is classified as a Class III antiarrhythmic agent. It shows rate-dependent inhibition of the rapid Na+ current, inhibits α and β-adrenergic receptors like Class II agents, exhibits...

YN321957 Thrombin Receptor Activator... 141685-53-2

Thrombin Receptor Activator for Peptide 5 (TRAP-5) is also called Coagulation Factor II Receptor (1-5) orProteinase Activated Receptor 1(1-5), used in the research of coronary heart disease (CHD).

YN371024 Pitavastatin lactone 141750-63-2

Pitavastatin lactone is a major metabolite of Pitavastatin in humans. Pitavastatin is a potent competitive inhibitor of HMG-CoA reductase little metabolized in hepatic microsomes.

YN322040 A81988 141887-34-5

A81988 is a potent, competitive, non-peptidic antagonist ofangiotensin AT1receptors.

YN361045 Catestatin 142211-96-9

Catestatin is a 21-amino acid residue, cationic and hydrophobic peptide. Catestatin is an endogenous peptide that regulates cardiac function and blood pressure. Catestatin is a non-competitivenicotinicantagonist acting through nicoti...

YN371094 Carvedilol metabolite 4-Hydr... 142227-49-4

4-Hydroxyphenyl Carvedilol is a metabolite of Carvedilol, which is a nonselective beta blocker/alpha-1 blocker.

YN1570014 GP531 142344-87-4

GP531 is a potent, second-generationadenosineregulating agent, is pharmacologically silent under basal conditions but increases localized endogenous adenosine during ischemia.

YN480157 Anti-Heart Failure Agent 1 142648-47-3

Anti-Heart Failure Agent 1 an orally available compound suitable for the treatment of heart failure without inducing nausea, vomiting and restlessness.

YN482419 Salvianolic acid D 142998-47-8

Salvianolic acid D, isolated fromSalvia miltiorrhiza, is a potential antiplatelet activity compound.

YN483628 Quercetin-3-O-D-glucosyl]-(... 143016-74-4

Quercetin-3-O-D-glucosyl]-(1-2)-L-rhamnoside is main antioxidant from Shuxuening, an herbal medicines injection.

YN370460 Cerivastatin sodium 143201-11-0

Cerivastatin sodium is a synthetic lipid-lowering agent and a highly potent, well-tolerated and orally activeHMG-CoA reductaseinhibitor, with a Ki of 1.3nM/L. Cerivastatin sodium reduces low-density lipoprotein cholesterol lev...

YN480390 CE3F4 143703-25-7

CE3F4 is a selective antagonist of exchange protein directly activated by cAMP (Epac1), with IC50s of 10.7μM and 66μM for Epac1 and Epac2(B), respectively.

YN481666 Aglafoline 143901-35-3

Aglafoline inhibits in a selective and concentration-dependent manner the aggregation and ATP release reaction induced in washed rabbit platelets by PAF (platelet-activating factor). The IC50 values of Aglafoline on PAF (3...

YN321036 Eprosartan mesylate 144143-96-4

Eprosartan is a nonpeptide angiotensin II receptor antagonist, [3H]-eprosartan binds to the AT1 receptor with KD of 0.83 nM in rat vascular smooth muscle cells.