YN360041 Dofetilide N-oxide 144449-71-8

Dofetilide N-oxide (UK-116856) is a metabolite of Dofetilide. Dofetilide is a class III antiarrhythmic agent that blockspotassium channels.

YN320058 Landiolol hydrochloride 144481-98-1

Landiolol hydrochloride is a drug which acts as a highly cardioselective, ultra short-acting beta blocker.

YN300048 Tirofiban 144494-65-5

Tirofiban(L700462;MK383) is a potent non-peptide, glycoprotein IIb/IIIa (integrins alphaIIbbetaIII) antagonist Tirofiban hydrochloride monohydrate blocks platelet aggregation and thrombus formation. Tirofiban is an antithr...

YN321101 Olmesartan 144689-24-7

Olmesartan medoxomil is a potent and selective angiotensin AT1 receptor inhibitor with IC50 of 66.2 μM.

YN321103 Olmesartan medoxomil 144689-63-4

Olmesartan Medoxomil (CS-866) is a selective angiotensin II type 1 (AT(1)) receptor antagonist, used in the treatment of high blood pressure.

YN320812 Telmisartan 144701-48-4

Telmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension.

YN320026 SL910102 144756-71-8

SL910102 is a nonpeptideangiotensin AT1 receptorantagonist.

YN321155 Candesartan Cilexetil 145040-37-5

Candesartan Cilexetil is an angiotensin II receptor antagonist with IC50 of 0.26 nM, used in the treatment of hypertension.

YN310087 Bisindolylmaleimide X hydroc... 145317-11-9

Bisindolylmaleimide X hydrochloride (BIM-X hydrochloride) is a potent and selectiveprotein kinase C (PKC)inhibitor. Bisindolylmaleimide X hydrochloride is a potentcyclin-dependent kinase 2 (CDK2)antagonist with an IC50 of...

YN481219 4-Acetylsimvastatin 145576-25-6

4-Acetylsimvastatin is an acetylated simvastatin. Simvastatin is a competitive inhibitor of HMG-CoA reductase with a Kiof 0.2nM.

YN371197 Cerivastatin 145599-86-6

Cerivastatin is a synthetic lipid-lowering agent and a highly potent, well-tolerated and orally activeHMG-CoA reductaseinhibitor, with a Ki of 1.3nM/L. Cerivastatin reduces low-density lipoprotein cholesterol levels. Cerivast...

YN481658 SC-52012 145643-15-8

HY-19163 is an orally active fibrinogen receptor antagonist, with antiplatelet activities.

YN321361 Tasosartan 145733-36-4

Tasosartan is a long-actingangiotensin II(AngII)receptorantagonist.

YN373993 NEP-IN-2 145775-14-0

NEP-IN-2 is an inhibitor ofneutral endopeptidase, used in the research of proliferation in atherosclerosis, restenosis.

YN370188 SCH 42495 racemate 145841-10-7

SCH 42495 racemate is the racemate of SCH 42495. SCH 42495 is an orally active neutral metalloendopeptidase (NEP) inhibitor with antihypertensive effect. SCH 42495 is the orally active ethylester prodrug of SCH 42354.

YN483783 Mas7 145854-59-7

Mas7 (Mastoparan 7), a structural analogue of mastoparan, is an activator of heterotrimericGi proteins and its downstream effectors.

YN360530 JTV-519 free base 145903-06-6

JTV-519 free base (K201 free base) is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and a partial agonist of ryanodine receptors in striated muscle. Antiarrhythmic and cardioprotective ...

YN484036 Activated Protein C (390-40... 146340-20-7

Activated Protein C (390-404), human is a peptide of the activated protein C (a vitamin K-dependent serine protease), potently inhibits APC anticoagulant activity.

YN440294 Tyrphostin AG1296 146535-11-7

Tyrphostin AG 1296 is an inhibitor of PDGFR with IC50 of 0.3-0.5 μM, no activity to EGFR.

YN320220 ZD 7155(hydrochloride) 146709-78-6

ZD 7155 hydrochloride is an angiotensin II receptor type 1 (AT1 receptor) antagonist.