YN360626 Rosuvastatin Calcium 147098-20-2

Rosuvastatin Calcium is a competitive inhibitor of HMG-CoA reductase with IC50 of 11 nM in a cell-free assay.

YN320931 Azilsartan 147403-03-0

Azilsartan is an angiotensin II type 1 (AT1) receptor antagonist with IC50 of 2.6 nM.

YN370865 Pyripyropene A 147444-03-9

Pyripyropene A is a potent and selectivesterol O-acyltransferase 2 (SOAT2)/acyl-coenzyme A:cholesterol acyltransferase 2 (ACAT2)inhibitor, with an IC50 of 0.07 µM. Pyripyropene A attenuates hypercholesterolemia and ath...

YN321323 Bosentan 147536-97-8

Bosentan is a competitive and dual antagonist ofendothelin-1 (ET)for the ETA and ETBreceptors with Kiof 4.7nM and 95nM in human SMC, respectively.

YN322028 MG 1 148274-76-4

MG 1 is an α1adrenergic receptorantagonist.

YN300008 Fradafiban 148396-36-5

Fradafiban is a nonpeptide platelet glycoprotein IIb/IIIa antagonist, which binds to the human platelet GP IIb/IIIa complex with a Kdvalue of 148nM.

YN320549 GR 125743 148547-33-5

GR 125743 is a selective5-HT1B/1Dreceptor antagonist, with aKdof 0.61nM for h5-HT1B. GR 125743 is used for the research of Parkinson's disease and cardiovascular diseases.

YN251671 EGCG Octaacetate 148707-39-5

EGCG Octaacetate is a prodrug of Green tea epigallocatechin-3-gallate (EGCG), utilized to enhance the stability and bioavailability of EGCG in vivo. EGCG Octaacetate has high efficacy, bioavailability, anti-oxidation a...

YN330363 Carboxy-PTIO potassium 148819-94-7

Carboxy-PTIO potassium is a potentnitric oxide (NO)scavenger that can make a quick reaction with NO to produce NO2. Carboxy-PTIO potassium can prevent hypotension and endotoxic shock through the direct scavenging action a...

YN321399 Ivabradine hydrochloride 148849-67-6

Ivabradine HCl, a new If inhibitor with IC 50 of 2.9 μM which acts specifically on the pacemaker activity of the sinoatrial node, is a pure heart rate lowering agent.

YN481731 Dexrazoxane hydrochloride 149003-01-0

Dexrazoxane HCl (ICRF-187, ADR-529) is an intracellular iron chelator, which decreases the formation of superoxide radicals, used as a cardioprotective agent also an inhibitor of topoisomerase II

YN320178 QF0301B 149247-12-1

QF0301B is anα1 adrenergic receptorantagonist and a low α2 adrenoceptor, 5-HT2A, and histamine H1 receptor blocker.

YN372296 Sacubitril 149709-62-6

Sacubitril (AHU-377) is a potent NEP inhibitor with an IC50 of 5nM. Sacubitril (AHU-377) is a component of the heart failure medicine LCZ696.

YN360653 Azimilide Dihydrochloride 149888-94-8

Azimilide Dihydrochloride (NE-10064 Dihydrochloride) is a class III antiarrhythmic compound, inhibits I(Ks) and I(Kr) in guinea-pig cardiac myocytes and I(Ks) (minK) channels expressed in Xenopus oocytes.

YN360652 Azimilide 149908-53-2

Azimilide(NE-10064) is a class III antiarrhythmic compound, inhibits I(Ks) and I(Kr) in guinea-pig cardiac myocytes and I(Ks) (minK) channels expressed in Xenopus oocytes.

YN321210 Elisartan 149968-26-3

Elisartan is an orally active non-peptide pro-drug ofangiotensin II AT1 receptorantagonist HN-12206, and shows anti-hypertension activities.

YN321207 Terbogrel 149979-74-8

Terbogrel is an orally availablethromboxane A2 receptorantagonist and athromboxane A2 synthaseinhibitor, with bothIC50s of about 10nM.

YN320957 Prasugrel 150322-43-3

Prasugrel is a thienopyridine ADP receptor (P2Y12) antagonist, used for the reduction of thrombotic cardiovascular events.

YN360499 Levamlodipine besylate 150566-71-5

Levamlodipine besylate ((S)-Amlodipine besylate) is a powerful dihydropyridinecalcium channelblocker, possessing vasodilation properties and used in the treatment of hypertension and angina.

YN321100 Tolvaptan 150683-30-0

Tolvaptan is an orally effective nonpeptide arginine vasopressin V2 receptor antagonist with IC50 of 3 nM, used to treat hyponatremia.