YN372223 Elvitegravir 697761-98-1

Elvitegravir (GS-9137, JTK-303) is an HIV integrase inhibitor for HIV-1 IIIB, HIV-2 EHO and HIV-2 ROD with IC50 of 0.7 nM, 2.8 nM and 1.4 nM in cell-free assays, respectively.

YN250636 Temsavir 701213-36-7

Temsavir (BMS-626529) is a novel small-molecule HIV-1 attachment inhibitor active against both CCR5- and CXCR4-tropic viruses.

YN330372 STING agonist-1 702662-50-8

STING agonist-1 (G10) is human-specificSTINGagonist that elicits antiviral activity against emerging Alphaviruses. G10 potently blocks replication of Alphavirus species Venezuelan Equine Encephalitis Virus (VEEV) withI...

YN250640 CHIR-090 728865-23-4

CHIR-090 is a potent, slow, tight-binding inhibitor of theLpxCdeacetylase. It binds toE. coliLpxCwith a Ki of 4.0nM.

YN371368 BMS-707035 729607-74-3

BMS-707035 is a specific HIV-I integrase (IN) inhibitor with IC50 of 15 nM. Phase 2.

YN250500 T-705RTP 740790-94-7

T-705RTP is a selective and GTP-competitiveinfluenza virus RNA polymeraseinhibitor with an IC50 of 0.14μM and a Ki of 1.52μM. T-705RTP is the active triphosphate metabolite of T-705 and has potent anti-influenza ...

YN251694 Tropodithietic acid 750590-18-2

Tropodithietic acid is a sulfur-containing antibiotic produced by the marine bacteriumPhaeobacter inhibens. Tropodithietic acid exhibits a strong antibiotic activity against a broad spectrum of bacteria including alpha- and gammaproteo...

YN250765 Solithromycin 760981-83-7

Solithromycin, belonging to the well-known class of macrolide antibiotics that also includes azithromycin, is a potent bacterial protein synthesis inhibitor.

YN250353 ML406 774589-47-8

ML406 is a small molecule probe that showsanti-tubercularactivity viaM.tuberculosisBioA(DAPA synthase) enzyme inhibition with an IC50 of 30nM.M.tuberculosisBioA is an enzyme involved in biotin biosynthesis inM.tuberculosis.

YN251519 Dehydroandrographolide succin... 786593-06-4

A herb extraction

YN250205 MCB-3681 790704-42-6

MCB-3681 is the antibacterial Oxaquin's active substance, active against gram-positive bacterium.

YN484268 Itch-Targeting Compound 1 793674-76-7

Itch-Targeting Compound 1 is an anti-itching agent.

YN251822 PBP10 794466-43-6

PBP10 is a cell permeable and selective gelsolin-derived peptide inhibitor offormyl peptide receptor 2 (FPR2)over FPR1. PBP10 is a 10-AA peptide with rhodamine conjugated at its N terminus, exerts bactericidal activity agai...

YN250185 Obatoclax 803712-67-6

Obatoclax (GX15-070), a BH3 mimetic, is a pan-BCL-2family proteins inhibitor with a Ki of 220nM for BCL-2. Obatoclax inducesautophagy-dependent cell death and targets cyclin D1 for proteasomal degradation. Obatoclax has an...

YN250184 Obatoclax Mesylate 803712-79-0

Obatoclax Mesylate (GX15-070) is an antagonist of Bcl-2 with Ki of 0.22 μM in a cell-free assay, can assist in overcoming MCL-1 mediated resistance to apoptosis. Phase 3.

YN360316 Resolvin D2 810668-37-2

Resolvin D2 is a metabolite of docosahexaenoic acid (DHA), with anti-inflammatory, anti-infective activities. Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis. Resolvin D2 is a remarkably potent inhib...

YN250064 PSI-6130 817204-33-4

PSI-6130 is a potent and selective inhibitor ofHCV NS5B polymerase, and inhibits HCV replication with a mean IC50 of 0.6μM.

YN360582 SN 2 823218-99-1

SN 2 is a potent activator of TRPML3ion channel with an EC50 of 1.8μM. SN 2 also acts as a potent inhibitor of Dengue virus 2 (DENV2) and Zika virus (ZIKV).

YN251817 LF11 832729-13-2

LF11 is a peptide withantibacterialactivity.

YN251816 Lauryl-LF 11 832729-14-3

Lauryl-LF 11, N-terminally acylated analogue of LF11, is a peptide withantibacterialactivity.