YN250442 MAC-545496 838810-96-1

MAC-545496 is a nanomolar glycopeptide-resistance-associated protein R(GraR) inhibitor with strong binding affinity to the full-length GraR protein (Kd ≤ 0.1 nM). MAC-545496 can reverse β-lactam resistance in methic...

YN250674 Helioxanthin 8-1 840529-13-7

Helioxanthin 8-1 is an analogue of helioxanthin, exhibites significant in vitro anti-HBV/HCV/HSV-1/HIV activity with EC50 of >5/10/1.4/15 uM.

YN250599 Amenamevir 841301-32-4

Amenamevir is a potent helicase-primase inhibitor and a novel class of antiviral agent.

YN250610 Bedaquiline 843663-66-1

Bedaquiline(TMC207; R207910) is an anti-tuberculosis drug which selectively inhibit the mycobacterial energy metabolism i.e. ATP synthesis and found to be effective against all states of Mycobacterium tuberculosis.

YN250611 Bedaquiline fumarate 845533-86-0

Bedaquiline fumarate, an oral diarylquinoline, is a bactericidal antimycobacterial drug. It is a proton-translocating ATP synthetase inhibitor.

YN250420 dmDNA31 845625-44-7

dmDNA31 is a rifamycin-class antibiotic that inhibits bacterial DNA-dependent RNA polymerase with potent bactericidal activity against S.aureus.

YN250042 BRD-6929 849234-64-6

BRD-6929 (Cpd-60) is a brain-penetrant, selective inhibitor of HDAC1 and HDAC2(IC50= 1 and 8nM), extracted from patent US2018360927. BRD-6929 (Cpd-60) shows high-affinity to HDAC1 and HDAC2 with Kiof 0.2 ...

YN370243 Danoprevir 850876-88-9

Danoprevir(ITMN-191) is a peptidomimetic inhibitor of the NS3/4A protease of hepatitis C virus (HCV) with IC50 of 0.2-3.5 nM, inhibition effect for HCV genotypes 1A/1B/4/5/6 is ~10-fold higher than 2B/3A. Phase 2.<...

YN373321 20(21)-Dehydrolucidenic acid ... 852936-69-7

20(21)-Dehydrolucidenic acid A is a triterpenoid isolated from the fruiting body of the fungusGanoderma sinense. 20(21)-Dehydrolucidenic acid A has weakanti-HIV-1 proteaseactivity.

YN250604 Tedizolid 856866-72-3

Tedizolid phosphate is a novel oxazolidinone with activity against Gram-positive pathogens.

YN250605 Tedizolid phosphate 856867-55-5

Tedizolid is an oxazolidinone-class antibiotic. Tedizolid phosphate is a phosphate ester prodrug of the active compound tedizolid.

YN250188 TMC353121 857066-90-1

TMC353121 is a potent respiratory syncytial virus (RSV) fusion inhibitor withpEC50of 9.9.

YN410021 Triphala 857906-76-4

Triphala, an Ayurvedic polyherbal formulation comprising of equiproportional fruit parts ofTerminalia chebula,Terminalia bellerica, and Phyllanthus emblica. Triphala inhibitsNF-κBactivation. Triphala exertsantifungalaction. An...

YN250224 RSV-IN-1 861139-16-4

RSV-IN-1 is a human respiratory syncytical virus(hRSV)inhibitor, with an IC50 of 0.11μM.

YN250427 Ganoderic acid TR 862893-75-2

Ganoderic acid TR is a broad-spectrum inhibitor againstinfluenza neuraminidases (NAs), particularly H5N1 and H1N1 neuraminidases. TheIC50 values of 10.9 and 4.6μM, respectively.

YN250176 Salicyl-AMS 863238-55-5

Salicyl-AMS is amycobactin biosynthesisinhibitor which can also inhibitM. tuberculosisgrowthin vitrounder iron-limited conditions.

YN482524 Dehydroandrographolide succin... 863319-40-8

Dehydro and rographolide succinate (potassium sodium salt), extracted from herbal medicine and rographis paniculata(Burm f) Nees, is widely used for the treatment of viral pneumonia and viral upper respiratory tract infections because ...

YN250625 PSI-6206 863329-66-2

PSI-6206 (RO-2433, GS-331007) is a potent inhibitor of the hepatitis C virus RNA-dependent RNA polymerase, targeting NS5B polymerase.

YN250687 Fluralaner 864731-61-3

Fluralaner is a systemic insecticide and acaricide that is administered orally.

YN280051 EACC 864941-31-1

EACC is a reversibleautophagyinhibitor, which can block autophagic flux. EACC selectively inhibits the translocation of autophagosome-specific SNARE Stx17 thereby blocking autophagosome-lysosome fusion.