YN250637 Fostemsavir 864953-29-7

Fostemsavir (BMS-663068, Rukobia), the phosphonooxymethyl prodrug of BMS626529, is an attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells with EC50 of < 10 nM.

YN250638 Fostemsavir Tris 864953-39-9

Fostemsavir Tris (BMS-663068 (Tris)) is the phosphonooxymethyl prodrug of BMS-626529. Fostemsavir Tris (BMS-663068 (Tris)) is a novel attachment inhibitor that targetsHIV-1gp120 and prevents its binding to CD4+T cell...

YN250074 KKL-35 865285-29-6

KKL-35 inhibits the trans-translation tagging reaction with an IC50 of 0.9 µM. It has broad-spectrum antibiotic activity.

YN250100 Islatravir 865363-93-5

Islatravir (MK-8591) is a potent anti-HIV-1agent, acting as a nucleosidereverse transcriptaseinhibitor, with EC50s of 0.068nM, 3.1nM and 0.15nM for HIV-1 (WT), HIV-1 (M184V), HIV-1 (MDR), respectively.

YN370254 Narlaprevir 865466-24-6

Narlaprevir is a potent, selective, orally bioavailable NS3 protease inhibitor(Ki=6nM; EC90=40nM)

YN250598 Tecovirimat 869572-92-9

Tecovirimat (Arestvyr, SIGA-246, ST-246, TPOXX) is an antiviral that inhibits the egress of orthopoxviruses by targeting viral p37 protein orthologs. Tecovirimat is developed for the treatment of smallpox infecti...

YN250597 Radezolid 869884-78-6

Radezolid (RX-1741) is a oxazolidinone antibiotic. Radezolid is active againstStaphylococcus,Chlamydia, and Legionellaspecies, and remains active against Linezolid-resistant strains.

YN370280 Raltegravir potassium salt 871038-72-1

Raltegravir Potassium is the orally bioavailable potassium salt of raltegravir, the first approved human immunodeficiency virus type 1 (HIV-1) integrase inhibitor.

YN481217 (R)-​Linezolid 872992-20-6

(R)-Linezolid is an impurity of Linezolid (PNU-100766). Linezolid, the first member of the class of oxazolidinone synthetic antibiotic, acts by inhibiting the initiation of bacterial protein synthesis.

YN250757 Fidaxomicin 873857-62-6

Fidaxomicin is a narrow spectrum macrocyclic antibiotic that inhibits RNA polymerase sigma subunit.

YN250169 RO-9187 876708-03-1

RO-9187 is a potent inhibitor ofHCVvirus replication with an IC50 of 171nM.

YN250050 Filibuvir 877130-28-4

Filibuvir is a potent, selective non-nucleoside inhibitor (NNI) of theHCV nonstructural 5B protein (NS5B) RNA-dependent RNA polymerase, and it binds noncovalently in the “Thumb 2” pocket of NS5B. In vitro, filibuvi...

YN250503 LtaS-IN-1 877950-01-1

LtaS-IN-1 (compound 1771) is a potent small-molecule inhibitor ofLipoteichoic acid (LTA) synthesisin multidrug-resistant (MDR)E. faecium and by altering the cell wall morphology. LtaS-IN-1 alone inhibitsEnterococcus.spp28 ...

YN250780 Walrycin B 878419-78-4

Walrycin B is an antibacterial compound and a potent inhibitor of WalR targeting the WalR response regulator.

YN250658 Bismuth subcitrate potassium 880149-29-1

Bismuth Subcitrate is an antibiotic used to treat stomach ulcers associated with Helicobacter pylori, a bacterial infection.

YN482276 4-Methylumbelliferyl-β-D-gl... 881005-91-0

4-Methylumbelliferyl-β-D-glucuronide hydrate is a fluorogenic substrat (λex=362nM , λem=445nM).

YN310082 OSS_128167 887686-02-4

OSS_128167 is a specific SIRT6 inhibitor with IC50 values of 89, 1578 and 751 μM for SIRT6, SIRT1 and SIRT2, respectively.

YN250507 SARS-CoV-IN-1 888958-25-6

SARS-CoV-IN-1 is an effective inhibitor ofSARS-CoVreplication. SARS-CoV-IN-1 shows anti-Coronavirus activity with an EC50 of 4.9μM in Vero cells. SARS-CoV-IN-1 inhibits the 3D7 and W2 strains ofP. fa...

YN250508 SARS-CoV-IN-2 888958-26-7

SARS-CoV-IN-2 is an effective inhibitor ofSARS-CoVreplication. SARS-CoV-IN-2 shows anti-Coronavirus activity with an EC50 of 1.9μM in Vero cells. SARS-CoV-IN-2 inhibits the 3D7 and W2 strains ofP. fa...

YN250509 SARS-CoV-IN-3 888958-27-8

SARS-CoV-IN-3 is an effective inhibitor ofSARS-CoVreplication. SARS-CoV-IN-3 shows anti-Coronavirus activity with an EC50 of 3.6μM in Vero cells. SARS-CoV-IN-3 inhibits the 3D7 and W2 strains ofP. f...