YN321992 TRAP-6 amide 141923-40-2

TRAP-6 amide is aPAR-1 thrombin receptoragonist peptide.

YN250909 (-)-Ketoconazole 142128-57-2

(-)-Ketoconazole ((-)-R 41400) is one of the enantiomer of Ketoconazole. Ketoconazole is a racemic mixture of two enantiomers, levoketoconazole ((2S,4R)-(−)-ketoconazole) and dextroketoconazole ((2R,4S)-(+)-ketoconazole).

YN371094 Carvedilol metabolite 4-Hydr... 142227-49-4

4-Hydroxyphenyl Carvedilol is a metabolite of Carvedilol, which is a nonselective beta blocker/alpha-1 blocker.

YN483991 CEF8, Influenza Virus NP... 142479-13-8

CEF8, Influenza Virus NP (383-391), an influenza A virus nucleoprotein containing residues 383 to 391, is the most important HLA-B*2705-restricted epitope in the nucleoprotein of influenza A viruses and is associated with esc...

YN483785 p2Ca 142606-55-1

p2Ca, an 8-mer peptide, is a lig and that is naturally processed and presented to the Ld-alloreactive T cell clone, 2C.

YN483370 Timosaponin B III 142759-74-8

Timosaponin B III is a major bioactive steroidal saponin isolated fromAnemarrhena asphodeloidesBge, and exhibits anti-inflammatory, anti-platelet aggregative and anti-depressive effects .

YN480402 Anakinra 143090-92-0

Anakinra (Raleukin) is a recombinant, nonglycosylated humaninterleukin-1 receptor (IL-1R)antagonist. Anakinra is the first biological agent to block the pro-inflammatory effects.

YN483027 Neotuberostemonine 143120-46-1

Neotuberostemonine, one of the main antitussive alkaloids in the root of Stemona tuberosa Lour, attenuates bleomycin-induced pulmonary fibrosis by suppressing the recruitment and activation of macrophages.

YN373434 NIM811 143205-42-9

NIM811 ((Melle-4)cyclosporin; SDZ NIM811) is an orally bioavailablemitochondrial permeability transition and cyclophilindual inhibitor, which exhibits potent in vitro activity against hepatitis C virus (HCV).

YN370185 S-methyl-KE-298 143584-75-2

S-methyl-KE-298 is an active metabolite of KE-298. KE-298 inhibits matrix metalloproteinase (MMP-1) production from rheumatoid arthritis (RA) synovial cells.

YN371179 Piclamilast 144035-83-6

Piclamilast (RP 73401) is aphosphodiesterase 4 (PDE4)inhibitor, with IC50 values of 16nM and 2nM in pig aorta and eosinophil soluble, respectively.

YN372533 FK706 144055-55-0

FK706 is a potent, slow-binding and competitive inhibitor ofhuman neutrophil elastasewith an IC50 of 83nM and a Ki of 4.2nM. FK706 also inhibitsmouse neutrophil elastase and porcine pancreatic elastasewith IC50s of 22nM and...

YN410137 Licochalcone D 144506-15-0

Licochalcone D, a flavonoid compound mainly existing in the root ofGlycyrrhiza inflate, is a potent inhibitor ofNF-kappaB (NF-κB) p65. Licochalcone D possesses antioxidant, anti-inflammatory, anti-cancer properties.

YN320243 GR 113808 144625-51-4

GR 113808 is a potent and highly selective5-HT4receptorantagonist (pKb= 8.8). GR 113808 shows 300-fold selectivity over 5-HT1A, 5-HT1B, 5-HT2A, 5-HT2C and 5-HT3receptors.

YN483984 TNF-α (10-36), human 144796-70-3

TNF-α (10-36), human is a peptide of human TNF-α.

YN484002 TNF-α (31-45), human 144796-71-4

TNF-α (31-45), human is a peptide of tumor necrosis factor-α.

YN484012 TNF-α (46-65), human 144796-72-5

TNF-α (46-65), human is a peptide of TNF-α.

YN330272 Resiquimod 144875-48-9

Resiquimod is an immune response modifier that acts as a potent TLR 7/8 agonist. Phase 2.

YN320328 Iodophenpropit dihydrobromide 145196-87-8

Iodophenpropit dihydrobromide is a potent and selectivehistamine H3 receptorantagonist. The binding of [125I]Iodophenpropit is selective, saturable, readily reversible, and of high affinity (KD0.32nM).

YN321844 CALP1 145224-99-3

CALP1 is acalmodulin (CaM)agonist (Kdof 88 µM) with binding to theCaMEF-h and /Ca2+-binding site. CALP1 blocks calcium influx and apoptosis (IC50 of 44.78 µM) through inhibition ofcalcium channelopening. CALP1 bl...