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Inflammation/Immunology

Chemical structure

Cat.No.

Product Name

CAS no.

Target

  • YN320609 Antileukinate 138559-60-1

    Antileukinate, a hexapeptide, is a potent inhibitor ofCXC-chemokine receptor (CXCR). Antileukinate inhibits neutrophil chemotaxis and activation. Antileukinate can be used for the research of acute inflammation and injury .

  • YN321827 Galantide 138579-66-5

    Galantide, a non-specificgalanin receptorantagonist, is a peptide consisting of fragments of galanin and substance P. Galantide recognizes two classes of galanin binding sites (KD<0.1nM and ~6nM) in the rat hypothalamus. Galanti...

  • YN320387 Icatibant acetate 138614-30-9

    Icatibant Acetate acts as an antagonist of the bradykinin B2 receptor and is used in the treatment of hereditary angioedema.

  • YN360632 Pantoprazole sodium 138786-67-1

    Pantoprazole is a proton pump inhibitor drug that inhibits gastric acid secretion. It works on gastric parietal cells to irreversibly inhibit (H+/K+)-ATPase function and suppress the production of gastric acid.

  • YN483214 Pasakbumin B 138809-10-6

    Pasakbumin B, a bioactive compound fromEurycoma longifoliaJack, exhibits potent antiulcer activity.

  • YN483894 OVA Peptide 257-264 138831-86-4

    OVA Peptide (257-264) is a class I (Kb)-restricted peptide epitope of OVA, an octameric peptide from ovalbumin presented by the class I MHC molecule, H-2Kb.

  • YN330585 Anemarsaponin B 139051-27-7

    Anemarsaponin B is a steroidal saponin isolated from the rhizomes ofA. asphodeloides(Liliaceae). Anemarsaponin B decreases the protein and mRNA levels ofiNOS and COX-2. Anemarsaponin B reduces the expressions and produc...

  • YN320146 Darbufelone 139226-28-1

    Darbufelone is a dual inhibitor of cellularPGF2α and LTB4production. Darbufelone potently inhibitsPGHS-2(IC50= 0.19μM) but is much less potent withPGHS-1(IC50=20μM).

  • YN320147 Darbufelone mesylate 139340-56-0

    Darbufelone mesylate (CI-1004 mesylate) is a dual inhibitor of cellularPGF2α and LTB4production. Darbufelone potently inhibitsPGHS-2(IC50= 0.19μM) but is much less potent withPGHS-1(IC50= 20μM).

  • YN320033 CP-96486 139401-45-9

    CP-96486 is a potent and orally active leukotriene D4(LTD4)/platelet activating factor (PAF) receptor antagonist with Kis of 20 and 24nM, respectively.

  • YN251824 PR-39 139637-11-9

    PR-39, a natural proline- and arginine-rich antibacterial peptide, is a noncompetitive, reversible and allostericproteasomeinhibitor. PR-39 reversibly binds to the α7 subunit of the proteasome and blocks degradation of NF-κB ...

  • YN482961 Tenuifoliside C 139726-37-7

    Tenuifoliside C, isolated from polygala tenuifolia willd, significantly inhibits chlorzoxazone 6-hydroxylation catalyzed by CYP2E1.

  • YN483021 Palbinone 139954-00-0

    Palbinone is a terpenoid isolated from the roots ofPaeonia albifloraPallas, potently inhibits3α-hydroxysteroid dehydrogenase (3α-HSD), with an IC50 of 46nM. Anti-inflammatory activity.

  • YN250881 Pentosan Polysulfate Sodium 140207-93-8

    Pentosan Polysulfate Sodium is an orally bioavailable, semi-synthetic medication with anti-inflammatory and pro-chondrogenic properties. Pentosan Polysulfate Sodium also is a potent and selective anti-HIVagent. Pentosan Polys...

  • YN340040 RSVA405 140405-36-3

    RSVA405 is a potent, orally active activator ofAMPK, with an EC50 of 1μM. RSVA405 facilitates CaMKKβ-dependent activation of AMPK, inhibitsmTOR, and promotesautophagyto increase Aβ degradation. RSVA405 ha...

  • YN321492 Olopatadine hydrochloride 140462-76-6

    Olopatadine HCl is a histamine blocker and mast cell stabilizer with an IC50 of 559 μM for the release of histamine.

  • YN321788 TRAP-6 141136-83-6

    TRAP-6 (PAR-1 agonist peptide) is a protease-activated receptor 1(PAR1)agonist.

  • YN321995 Protease-Activated Receptor... 141136-85-8

    Protease-Activated Receptor-1, PAR-1 Agonist is a thrombin-specific, protease-activated receptor 1 (PAR-1)-specific agonist peptide.

  • YN481013 Microcolin B 141205-32-5

    Microcolin B is an extremely potent unusual acylpeptide, proline-containing potent immunosuppressant. Microcolin B is isolated from blue-green algaLyngbya majuscule.

  • YN260056 Tr-PEG5-OH 141282-24-8

    Tr-PEG5-OH is a non-cleavable 5 unit PEGADClinker used in the synthesis of antibody-drug conjugates (ADCs).

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