YN372287 Ranirestat 147254-64-6

Ranirestat (AS-3201) potent and orally activealdose reductase (AR)inhibitor with IC50s of 11nM and 15nM forrat lens AR and recombinant human AR, respectively, and a Ki of 0.38nM forrecombinant human AR. Ranirestat ha...

YN372745 Pitavastatin 147511-69-1

Pitavastatin (NK-104) is a potenthydroxymethylglutaryl-CoA (HMG-CoA) reductaseinhibitor. Pitavastatin inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8nM in HepG2 cells. Pitavastatin is an efficient hepato...

YN372744 Pitavastatin Calcium 147526-32-7

Pitavastatin calcium, a novel member of the medication class of statins, is a calcium salt formulation of pitavastatin which is a highly effective HMG-CoA reductase inhibitor.

YN373407 GDP-​α-D-​mannose disod... 148296-46-2

GDP-α-D-mannose disodium is the donor substrate for mannosyltransferases and the precursor of GDP-β-L-fucose. GDP-α-D-mannose disodium gives a competitive inhibition with respect to GTP (Ki14.7μM) and an uncompetiti...

YN420084 Chitosan oligosaccharide 148411-57-8

Chitosan oligosaccharide (COS) is an oligomer of β-(1→4)-linked D-glucosamine. Chitosan oligosaccharide (COS) activatesAMPK and inhibits inflammatory signaling pathways includingNF-κB and MAPKpathways.

YN330363 Carboxy-PTIO potassium 148819-94-7

Carboxy-PTIO potassium is a potentnitric oxide (NO)scavenger that can make a quick reaction with NO to produce NO2. Carboxy-PTIO potassium can prevent hypotension and endotoxic shock through the direct scavenging action a...

YN440439 CREBtide 149155-45-3

CREBtide, a synthetic 13 amino acid peptide, has been reported as aPKAsubstrate.

YN374360 N,N,O-Tridesmethylvenlafax... 149289-29-2

N,N,O-Tridesmethylvenlafaxine is an endogenous metabolite.

YN321999 Neuropeptide Y (3-36) (human... 150138-78-6

Neuropeptide Y (3-36) (human, rat), a neuropeptide Y (NPY) metabolite formed from dipeptidyl peptidase-4 (DPP4), is a selectiveY2 receptoragonist. Neuropeptide Y (3-36) (human, rat) is a NPY metabolite formed from dipeptidyl ...

YN483739 Pramlintide 151126-32-8

Pramlintide is a polypeptide analogue of human amylin. Pramlintide is an antidiabetic, is antineoplastic in colorectal cancer.

YN374141 2'-Deoxycytidine-5'-diphospha... 151151-32-5

2'-Deoxycytidine-5'-diphosphate trisodium salt is an endogenous metabolite.

YN481662 S-8921 151165-96-7

S-8921 is an ileal Na+/bile acid cotransporter (IBAT) inhibitor.

YN340135 AG-1478 153436-53-4

AG-1478 (Tyrphostin AG-1478) is a selective EGFR inhibitor with IC50 of 3 nM in cell-free assays, almost no activity on HER2-Neu, PDGFR, Trk, Bcr-Abl and InsR.

YN372290 LG100268 153559-76-3

LG100268 (LG268) is a potent, selective and orally activeretinoid X receptor (RXR)agonist withEC50values of 4nM, 3nM, and 4nM for RXR-α, RXR-β, and RXR-γ, respectively. LG100268 displays >1000-fold selectivi...

YN480095 Heparastatin 153758-25-9

Heparastatin is aheparanaseinhibitor.

YN321876 ANQ-11125 153966-48-4

ANQ-11125 is a potent and selective antagonist ofmotilin, with thepKdof 8.24. ANQ-11125 blocks motilide-induced contractions in vitro in the rabbit.

YN300078 Echistatin 154303-05-6

Echistatin, the smallest active RGD protein belonging to the family of disintegrins that are derived from snake venoms, is a potent inhibitor ofplatelet aggregation. Echistatin is a potent inhibitor ofbone resorptionin culture. Echist...

YN322052 L162441 154512-46-6

L162441 is anAngiotensin type 1 receptorantagonist.

YN372396 SB 204990 154566-12-8

SB 204990 is a potent and specific inhibitor of ATP citrate lyase(ACLY)enzyme.

YN320730 Olmesartan impurity 154709-18-9

Olmesartan impurity is an Olmesartan impurity. Olmesartan (RNH-6270) is anangiotensin II receptor (AT1R)antagonist has the potential for high blood pressure study.