YN372196 NVP-DPP728 dihydrochlori... 207556-62-5

NVP-DPP728 dihydrochloride is a potent, selective and orally active dipeptidyl peptidase IV (DPP-IV) inhibitor with a Ki of 11nM. NVP-DPP728 dihydrochloride can be used for the research of diabetes mellitus.

YN360827 Mitiglinide calcium hydrate 207844-01-7

Mitiglinide calcium hydrate is a drug for the treatment of type 2 diabetes; it is a highly selective KATP channel antagonist.

YN370494 Diprotin A TFA 209248-71-5

Diprotin A TFA (Ile-Pro-Ile TFA) is an inhibitor of dipeptidyl peptidase IV(DPP-IV).

YN370609 Hydroxypyruvic acid lithium h... 209728-15-4

Hydroxypyruvic acid lithium hydrate (β-Hydroxypyruvic acid lithium hydrate) is anintermediatein the metabolism of glycine, serine and threonine. Hydroxypyruvic acid lithium hydrate is asubstratefor serine-pyruvate aminotransferase an...

YN480419 Gemcabene calcium 209789-08-2

Gemcabene calcium (PD-72953 calcium), a first-in-class lipid-lowering agent, lowers low-density lipoprotein cholesterol (LDL-C), decreases triglycerides, and raises high-density lipoprotein cholesterol (HDL-C) and lowers pro-...

YN360516 Zonampanel 210245-80-0

Zonampanel (YM 872) is a selective antagonist of the glutamate receptor subtype, α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid(AMPA) receptor.

YN374219 N-Acetyl-L-arginine dihydra... 210545-23-6

N-Acetyl-L-arginine (dihydrate) is an endogenous metabolite.

YN482272 Cy5.5 210892-23-2

Cy5.5 (Sulfo-Cyanine5.5) is a near-infrared fluorescent dye (Ex=673nM, Em=707nM) used to label biological molecules, such as peptides, proteins, and oligonucleotides.

YN481402 Sobetirome 211110-63-3

Sobetirome (GC-1) is a thyroid hormone receptor β (TRβ)-specific agonist which bind selectively toTRβ-1with an EC50 of 0.16μM.

YN484302 BIBR 1087 SE 212321-78-3

BIBR 1087 SE is an intermediate metabolite of dabigatran etexilate.

YN321873 HS024 212370-59-7

HS024 is a selectiveMC4 receptorantagonist, with Kis of 0.29, 3.29, 5.45, and 18.6nM for MC4, MC5, MC3, and MC1, respectively. HS024 increase food intake.

YN484245 BM152054 213411-84-8

BM152054 can promote glucose utilization in peripheral tissues by enhancing insulin action.

YN370419 BMS493 215030-90-3

BMS493 is an inverse pan-retinoic acid receptor (RAR)agonist. BMS493 increases nuclear corepressor interaction withRARs. BMS493 also could prevent retinoic acid-induced differentiation.

YN380013 Rimacalib 215174-50-8

Rimacalib (SMP 114) is a Ca2+/calmodulin-dependent protein kinase II (CaMKII)inhibitor, with IC50s of ~1μM for CaMKIIαto ~30μM for CaMKIIγ.

YN370938 FR-190809 215589-63-2

FR-190809 is a potent, nonadrenotoxic, orally efficacious acyl-CoA:cholesterol O-acyltransferase (ACAT) inhibitor, with an IC50 of 45nM.

YN470022 1alpha, 25-Dihydroxy VD2-D... 216244-04-1

1alpha, 25-Dihydroxy VD2-D6 is a deuterated form of vitamin D.

YN484042 Apelin-13 217082-58-1

Apelin-13 is the endogenous lig and of the orphan G protein-coupled receptor APJ, activates APJ receptor with an EC50value of 0.37nM in CHO cells.

YN321220 WAY-151932 220460-92-4

WAY-151932 is avasopressin V2-receptoragonist with IC50 of 80.3nM and 778nM in human-V2binding and V1abinding assay.

YN320424 SR 146131 221671-61-0

SR 146131 is a potent, orally available, and selective nonpeptide (cholecystokinin 1) receptor agonist.

YN330370 BEC hydrochloride 222638-67-7

BEC HCl is a slow-binding, and competitive arginase inhibitor with Ki of 0.31 μM (pH7.5) and 0.4-0.6 μM for Arginase II and rat Arginase I, respectively.