YN380311 MAO-IN-1 124991-40-8

MAO-IN-1 is a monoamine oxidase B (MAO B) inhibitor with an IC50 of 20nM.

YN321965 Galanin (1-16), mouse, porcin... 125118-77-6

Galanin (1-16), mouse, porcine, rat is an agonist of the hippocampalgalanin receptor, with aKdof 3nM.

YN310250 Ro 31-8220 125314-64-9

Ro 31-8220 is a potentPKCinhibitor, with IC50s of 5, 24, 14, 27, 24 and 23nM for PKCα, PKCβI, PKCβII, PKCγ, PKCε and rat brain PKC, respectively. Ro 31-8220 also significantly inhibits MAPKAP-K1b...

YN483936 Ac-MBP (1-11) 125366-42-9

Ac-MBP 1-11, a short peptide sequence, is the major encephalitogenic epitope in myelin basic protein (MBP).

YN320866 TCN238 125404-04-8

TCN238 is an orally bioavailablemGlu4receptor positive allosteric modulator (PAM) with an EC50 of 1μM.

YN360489 Sibutramine hydrochloride mon... 125494-59-9

Sibutramine hydrochloride monohydrate is a novel5-HT(serotonin) and noradrenaline reuptake inhibitor (SNRI). TheIC50for Sibutramine block of voltage-gated K+channel (KV)4.3is 17.3μM.

YN321319 Rotigotine Hydrochloride 125572-93-2

Rotigotine Hydrochloride (N-0923 Hydrochloride) is a full agonist ofdopamine receptor, a partial agonist of the5-HT1A receptor, and an antagonist of theα2B-adrenergic receptor, with Kiof 0.71 nM, 4-15 nM, and 83 nM for t...

YN321986 Neuropeptide EI, rat 125934-45-4

Neuropeptide EI, rat displays functional melanin concentrating hormone (MCH)-antagonist and melanocyte-stimulating hormone (MSH) agonist activity in different behavioral paradigms.

YN321229 SCH-23390 hydrochloride 125941-87-9

SCH-23390 hydrochloride (R-(+)-SCH-23390 hydrochloride) is a potent and selectivedopamine D1-like receptorantagonist with Kis of 0.2nM and 0.3nM for theD1 and D5receptor, respectively. SCH-23390 hydrochloride is a potent...

YN360365 (R)-(+)-Anatabine 126454-22-6

(R)-(+)-Anatabine is an less active R-enantiomer of Anatabine. Anatabine is a potentα4β2 nAChRagonist. Anatabine inhibitsNF-κBactivation loweramyloid-β (Aβ)production by preventing the β-cleavage of amyloid precursor prot...

YN321851 Sarafotoxin S6a 126738-34-9

Sarafotoxin S6a, a sarafotoxin analogue, is aendothelin receptoragonist  and has anETA/ETBselectivity profile similar to that of Endothelin-3 (HY-P0204). Sarafotoxin S6a elicits the pig coronary artery with an EC50 value o...

YN483981 Myelin Basic Protein (MBP... 126768-94-3

Myelin Basic Protein MBP, the second most abundant protein in central nervous system myelin, is responsible for adhesion of the cytosolic surfaces of multilayered compact myelin. Myelin Basic Protein MBP performs an important fu...

YN483842 Locustatachykinin I 126985-97-5

Locustatachykinin I is a insect tachykinin-related peptide isolated fromLocusta migratoria. Locustatachykinin I exhibits sequence homologies with the vertebrate tachykinins. In Lacanobia, Locustatachykinin I is also a substrate for...

YN320590 CGP-42112 127060-75-7

CGP-42112 (CGP-42112A) is a potent Angiotensin-II subtype 2 receptor(AT2 R) agonist.

YN440355 H-89 127243-85-0

H-89 is a potent and selective inhibitor of cyclic AMP-dependent protein kinase (protein kinase A) with IC50 of 48nM and has weak inhibition on PKG, PKC, Casein Kinase, and others kinases.

YN483761 PACAP (1-27), human, ovin... 127317-03-7

Pituitary adenylate cyclase activating polypeptide (PACAP 1-27) is a potent PACAP receptor antagonist.

YN483495 Hydroxyl-​γ-​isosanshool 127514-62-9

Hydroxyl-γ-isosanshool is one of the major alkylamides in Z.bungeanum and Z.schinifoliumoils. Hydroxyl-γ-isosanshoo induces a numbing sensation.

YN320232 Fananserin 127625-29-0

Fananserin (RP 62203) is an orally bioavailable, potent and selective5-hydroxytryptamine2 (5-HT2)receptor antagonist, with a Ki of 0.37nM for the rat 5-HT2Areceptor. Fananserin also is a selectivedopamine D4receptor antagonist...

YN360196 CGP 37849 127910-31-0

CGP 37849 is a potent, competitive and orally activeN-methyl-D-aspartate (NMDA)receptor antagonist. CGP 37849 is an anticonvulsant in rodents and has antidepressant and anxiolytic-like effects.

YN380001 Ro 41-1049 hydrochloride 127917-66-2

Ro 41-1049 hydrochloride is a reversible and selective inhibitor ofmonoamine oxidase-A (MAO-A). An homogeneous population of high affinity binding sites for [3H]Ro 41-1049 is found in membrane preparations from human frontal cort...