Bisindolylmaleimide I
Cat. No. :YN310251
CAS No. :133052-90-1
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Product Name: | Bisindolylmaleimide I |
CAS NO.: | 133052-90-1 |
Chemical Name: | |
Synonyms: | GO 6850 , Bisindolylmaleimide I |
Molecular Weight: | 412.48 |
Molecular Formula: | C₂₅H₂₄N₄O₂ |
SMILES: | O=C(C(C1=CN(CCCN(C)C)C2=C1C=CC=C2)=C3C4=CNC5=C4C=CC=C5)NC3=O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Bisindolylmaleimide I (GF109203X) is a potent PKC inhibitor with IC50 of 20 nM, 17 nM, 16 nM, and 20 nM for PKCα, PKCβI, PKCβII, and PKCγ in cell-free assays, respectively, showing more than 3000-fold selectivity for PKC as compared to EGFR, PDGFR and insulin receptor. |
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