Ro 31-8220
Cat. No. :YN310250
CAS No. :125314-64-9
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order@ubiochem.com| Product Name: | Ro 31-8220 |
| CAS NO.: | 125314-64-9 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 457.55 |
| Molecular Formula: | C₂₅H₂₃N₅O₂S |
| SMILES: | NC(SCCCN1C=C(C2=C(C3=CN(C)C4=C3C=CC=C4)C(NC2=O)=O)C5=C1C=CC=C5)=N |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Ro 31-8220 is a potentPKCinhibitor, with IC50s of 5, 24, 14, 27, 24 and 23nM for PKCα, PKCβI, PKCβII, PKCγ, PKCε and rat brain PKC, respectively. Ro 31-8220 also significantly inhibits MAPKAP-K1b, MSK1, S6K1 and GSK3β (IC50s, 3, 8, 15, and 38nM, respectively), with no effect on MKK3, MKK4, MKK6 and MKK7. |
| IC50&Target: | |
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| References: |
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