Ro 32-0432 hydrochloride
Cat. No. :YN310095
CAS No. :1781828-85-0
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order@ubiochem.com| Product Name: | Ro 32-0432 hydrochloride |
| CAS NO.: | 1781828-85-0 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 489.01 |
| Molecular Formula: | C₂₈H₂₉ClN₄O₂ |
| SMILES: | O=C(C(C1=C(C[C@@H](CN(C)C)CC2)N2C3=C1C=CC=C3)=C4C5=CN(C)C6=C5C=CC=C6)NC4=O.[H]Cl |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Ro 32-0432 hydrochloride is a potent, selective, ATP-competitive and orally activePKCinhibitor. TheIC50 values of Ro 32-0432 hydrochloride forPKCα,PKCβI,PKCβII,PKCγ and PKCεare 9.3nM, 28nM, 30nM, 36.5nM and 108.3nM, respectively. Ro 32-0432 hydrochloride is also a selectiveG protein-coupled receptor kinase 5 (GRK5)inhibitor. Ro 32-0432 hydrochloride prevents T-cell activation and has the potential for chronic inflammatory and autoimmune diseases research. |
| IC50&Target: | |
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| References: |
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