K-252c
Cat. No. :YN310369
CAS No. :85753-43-1
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5mg
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Product Name: | K-252c |
CAS NO.: | 85753-43-1 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 311.34 |
Molecular Formula: | C₂₀H₁₃N₃O |
SMILES: | O=C1NCC2=C1C3=C(C4=C2C5=C(N4)C=CC=C5)NC6=C3C=CC=C6 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | K-252c, a staurosporine analog isolated fromNocardiopsis sp., is a cell-permeablePKCinhibitor, with an IC50 of 2.45 µM. K-252c induces apoptosis in human chronic myelogenous leukemia cancer cells. K-252c also inhibits β-lactamase, chymotrypsin, and malate dehydrogenase . |
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