O-Desmethyl Midostaurin
Cat. No. :YN310201
CAS No. :740816-86-8
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order@ubiochem.com| Product Name: | O-Desmethyl Midostaurin |
| CAS NO.: | 740816-86-8 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 556.61 |
| Molecular Formula: | C₃₄H₂₈N₄O₄ |
| SMILES: | O=C(N([C@@H]1C[C@]([H])(N2C3=C4C=CC=C3)O[C@](C)(N5C6=C2C4=C(C(NC7)=O)C7=C6C8=C5C=CC=C8)[C@@H]1O)C)C9=CC=CC=C9 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | O-Desmethyl Midostaurin (CGP62221; O-Desmethyl PKC412) is the active metabolite of Midostaurin (HY-10230) via cytochrome P450 liver enzyme metabolism. O-Desmethyl Midostaurin can be used as an indicator for Midostaurin metabolism in vivo. Midostaurin is a multi-targeted proteinkinaseinhibitor with IC50ranging from 22-500nM. |
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| References: |
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