A-3 hydrochloride
Cat. No. :YN310181
CAS No. :78957-85-4
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Product Name: | A-3 hydrochloride |
CAS NO.: | 78957-85-4 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 321.22 |
Molecular Formula: | C₁₂H₁₄Cl₂N₂O₂S |
SMILES: | O=S(C1=C2C=CC=C(Cl)C2=CC=C1)(NCCN)=O.[H]Cl |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | A-3 hydrochloride is a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of variouskinases. It against PKA (Ki=4.3 µM), casein kinase II (Ki=5.1 µM) and myosin light chain kinase (MLCK) (Ki=7.4 µM). A-3 hydrochloride also inhibits PKC and casein kinase I with Ki values of 47 µM and 80 µM, respectively. |
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