Bisindolylmaleimide IV
Cat. No. :YN310088
CAS No. :119139-23-0
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Product Name: | Bisindolylmaleimide IV |
CAS NO.: | 119139-23-0 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 327.34 |
Molecular Formula: | C₂₀H₁₃N₃O₂ |
SMILES: | O=C(C(C1=CNC2=C1C=CC=C2)=C3C4=CNC5=C4C=CC=C5)NC3=O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Bisindolylmaleimide IV (Arcyriarubin A) is a potentprotein kinase C (PKC)inhibitor, with IC50s ranging from 0.1 to 0.55μM. Bisindolylmaleimide IV also inhibits PKA (IC50=3.1-11.8μM). Bisindolylmaleimide IV is a potent, selective inhibitor of human cytomegalovirus(HCMV)replication in cell culture with an IC50 of 0.2μM. |
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