Ro 31-8220 mesylate
Cat. No. :YN310249
CAS No. :138489-18-6
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order@ubiochem.com| Product Name: | Ro 31-8220 mesylate |
| CAS NO.: | 138489-18-6 |
| Chemical Name: | |
| Synonyms: | Bisindolylmaleimide IX Mesylate |
| Molecular Weight: | 553.65 |
| Molecular Formula: | C₂₆H₂₇N₅O₅S₂ |
| SMILES: | NC(SCCCN1C=C(C2=C(C3=CN(C)C4=C3C=CC=C4)C(NC2=O)=O)C5=C1C=CC=C5)=N.CS(=O)(O)=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Bisindolylmaleimide IX (Ro 31-8220 Mesylate) is a pan-PKC inhibitor with IC50 of 5 nM, 24 nM, 14 nM, 27 nM, and 24 nM for PKC-α, PKC-βI, PKC-βII, PKC-γ, and PKC-ε, respectively, and also shows potent inhibition against MAPKAP-K1b, MSK1, GSK3β and S6K1. |
| IC50&Target: | |
| In Vitro: | |
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| References: |
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