(-)-Indolactam V
Cat. No. :YN310163
CAS No. :90365-57-4
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Product Name: | (-)-Indolactam V |
CAS NO.: | 90365-57-4 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 301.38 |
Molecular Formula: | C₁₇H₂₃N₃O₂ |
SMILES: | CC(C)[C@@H](C1=O)N(C)C2=C3C(NC=C3C[C@H](N1)CO)=CC=C2 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | (-)-Indolactam V is aPKCactivator, with Kis of 3.36nM, 1.03μM for η-CRD2 (PKCη surrogate peptide), γ-CRD2 (PKCγ surrogate peptide), and Kds of 5.5nM (η-C1B), 7.7nM (ε-C1B), 8.3nM (δ-C1B), 18.9nM (β-C1A-long), 20.8nM (α-C1A-long), 137nM (β-C1B), 138nM (γ-C1A), 213nM (γ-C1B), and has antitumor activity. |
IC50&Target: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: | |
References: |
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