Linifanib
Cat. No. :YN440404
CAS No. :796967-16-3
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order@ubiochem.com| Product Name: | Linifanib |
| CAS NO.: | 796967-16-3 |
| Chemical Name: | |
| Synonyms: | AL39324,RG3635 |
| Molecular Weight: | 375.40 |
| Molecular Formula: | C₂₁H₁₈FN₅O |
| SMILES: | O=C(NC1=CC=C(C2=C3C(N)=NNC3=CC=C2)C=C1)NC4=C(C=CC(C)=C4)F |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Linifanib (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR, CSF-1R, Flt-1/3 and PDGFRβ with IC50 of 4 nM, 3 nM, 3 nM/4 nM and 66 nM respectively, mostly effective in mutant kinase-dependent cancer cells (i.e. FLT3). Phase 3. |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
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