PLX647
Cat. No. :YN440293
CAS No. :873786-09-5
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order@ubiochem.com| Product Name: | PLX647 |
| CAS NO.: | 873786-09-5 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 382.38 |
| Molecular Formula: | C₂₁H₁₇F₃N₄ |
| SMILES: | FC(C1=CC=C(CNC2=NC=C(CC3=CNC4=NC=CC=C43)C=C2)C=C1)(F)F |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | PLX647 is an orally active, highly specific dualFMS and KITkinase inhibitor, with IC50s of 28 and 16nM, respectively. PLX647 shows selectivity for FMS and KIT over a panel of 400 kinases at a concentration of 1μM except FLT3 and KDR (IC50s=91 and 130nM, respectively). |
| IC50&Target: | |
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