Ki20227
Cat. No. :YN440092
CAS No. :623142-96-1
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order@ubiochem.com| Product Name: | Ki20227 |
| CAS NO.: | 623142-96-1 |
| Chemical Name: | |
| Synonyms: | KI-20227 |
| Molecular Weight: | 480.54 |
| Molecular Formula: | C₂₄H₂₄N₄O₅S |
| SMILES: | O=C(NC1=CC=C(C=C1OC)OC2=CC=NC3=CC(OC)=C(C=C23)OC)NC(C)C4=NC=CS4 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Ki20227 is an orally active and highly selective inhibitor of c-Fms tyrosine kinase(CSF1R) with IC50 of 2 nM, 12 nM, 451 nM and 217 nM for c-Fms, vascular endothelial growth factor receptor-2 (KDR/VEGFR-2), stem cell factor receptor (c-Kit), and platelet-derived growth factor receptor beta (PDGFRβ), respectively. |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
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