YN321324 Bosentan (hydrate) 157212-55-0

Bosentan is an endothelin (ET) receptor antagonist for ET-A and ET-B with Ki of 4.7 nM and 95 nM, respectively.

YN321208 L-159282 157263-00-8

L-159282 is a highly potent, orally active, nonpeptideangiotensin II receptorantagonist, with anti-hypertensive activity.

YN370184 Win 58237 158001-76-4

Win 58237 is a cyclic nucleotidephosphodiesterase (PDE)inhibitor, with Kiof 170nM for PDE V, possessing vasorelaxant activity.

YN330684 Nitroflurbiprofen 158836-71-6

Nitroflurbiprofen is acyclooxygenase(COX) inhibitor with nitric oxide (NO)-donating properties, modulates the increased intrahepatic vascular tone in portal hypertensive cirrhotic rats.

YN360689 Cariporide 159138-80-4

Cariporide is a selective and potent inhibitor of NHE1 with an IC50 of 30 nM for hNHE1 in CHO-K1 cells.

YN330026 L-NIO dihydrochloride 159190-44-0

L-NIO dihydrochloride is a potent, non-selective and NADPH-dependentnitric oxide synthase (NOS)inhibitor, with Kis of 1.7, 3.9, 3.9μM for neuronal (nNOS), endothelial (eNOS), and inducible (iNOS), respectively. L...

YN321812 A 779 159432-28-7

A 779 is a specific antagonist of G-protein coupled receptor (Mas receptor), which is anAng1-7 receptordistinct from the classical AngII.

YN372337 Napsagatran hydrate 159668-20-9

Napsagatran hydrate is a novel and specificthrombininhibitor.

YN322041 LY285434 159748-08-0

LY285434 is a suitableangiotensin II receptorantagonist.

YN371188 Melagatran 159776-70-2

Melagatran is a direct and orally active inhibitor ofthrombin, without interacting with any other enzymes in the coagulation cascade or fibrinolytic enzymes aside from thrombin. Melagatran does not require endogenous co-factors for its ...

YN321936 Adrenomedullin (AM) (22-52)... 159899-65-7

Adrenomedullin (AM) (22-52), human, an NH2 terminal truncated adrenomedullin analogue, is anadrenomedullin receptorantagonist, and also antagonizes the calcitonin generelated peptide (CGRP) receptor in the hindlimb vascular bed o...

YN483982 C-Reactive Protein (CRP)... 160369-86-8

C-Reactive Protein (CRP) 174-185 is the 174-185 fragment of C-Reactive Protein. C-Reactive Protein (CRP), the prototypic marker of inflammation, is a cardiovascular risk marker and may promote atherogenesis.

YN360110 CNS-5161 hydrochloride 160756-38-7

CNS-5161 hydrochloride is a novelNMDAion-channel antagonist that interacts with the NMDAreceptor/ion channel site to produce a noncompetitive blockade of the actions of glutamate.

YN480529 ETA antagonist 1 161801-60-1

ETA antagonist 1 is aETAselective antagonist with an IC50 of 0.08μM.

YN410072 Ezetimibe 163222-33-1

Ezetimibe is a potent, selective, cholesterol absorption inhibitor, used to lower cholesterol.

YN321975 Adrenomedullin (11-50), rat 163648-32-6

Adrenomedullin (11-50), rat is the C-terminal fragment (11-50) of rat adrenomedullin. Rat adrenomedullin induces a selective arterial vasodilation via CGRP1 receptors.

YN321235 Cangrelor tetrasodium 163706-36-3

Cangrelor is a potent, competitive P2Y12 receptor inhibitor that is administered by intravenous infusion and rapidly achieves near complete inhibition of ADP-induced platelet aggregation.

YN373235 Phosphoramidon Disodium 164204-38-0

Phosphoramidon Disodium Salt is a metalloendopeptidase inhibitor, widely used as a biochemical tool.

YN321098 Terutroban 165538-40-9

Terutroban is athromboxane-prostagl and in receptorantagonist.

YN483994 Proadrenomedullin (45-92), hu... 166798-69-2

Proadrenomedullin (45-92), human, a mid-regional fragment of proadrenomedullin (MR-proADM), comprises amino acids 45–92 of pre-proADM. Proadrenomedullin (45-92), human has a longer half-life, is relatively stable and is produce...