YN360569 Tenapanor 1234423-95-0

Tenapanor is an inhibitor of theNa+/H+exchanger NHE3 with IC50 values of 5 and 10nM against human and Rat NHE3, respectively.

YN374006 Soluble epoxide hydrolase inh... 1241826-88-9

Soluble epoxide hydrolase inhibitor is an inhibitor ofsoluble epoxide hydrolase, and inhibits human soluble epoxide hydrolase (h-sEH) withpIC50 of 8.4, extracted from patent WO 2010096722 A1, example 57.

YN360630 (3S,5R)-Rosuvastatin 1242184-42-4

(3S,5R)-Rosuvastatin is the (3S,5R)-enantiomer of Rosuvastatin. Rosuvastatin is a competitive HMG-CoAreductase inhibitor with an IC50 of 11nM. Rosuvastatin potently blockshuman ether-a-go-go related gene (hERG)current wit...

YN320692 Cimbuterol-D9 1246819-04-4

Cimbuterol-D9 is the deuterium labeled Cimbuterol. Cimbuterol is aβ-adrenergic agonist.

YN320726 Mabuterol-D9 1246819-58-8

Mabuterol-D9 is a deuterium labeled Mabuterol. Mabuterol is an agonist of theβ2-adrenergic receptor.

YN320642 Losartan (D4 Carboxylic Ac... 1246820-62-1

Losartan D4 Carboxylic Acid (E-3174 D4) is the deuterium labeled Losartan(EXP-3174), which is an angiotensin II receptor antagonist.

YN321499 Sotalol D6 hydrochloride 1246820-85-8

Sotalol D6 hydrochloride is a deuterium labeled Sotalol hydrochloride. Sotalol hydrochloride is a non-selective competitiveβ-adrenergic receptorantagonist that also exhibits Class III antiarrhythmic properties by its inhibition ofp...

YN300059 Eptifibatide acetate 1248559-53-6

Eptifibatide acetate is a cyclic heptapeptide, acts as a competitive antagonist for the activated plateletglycoprotein IIb/IIIa receptor, with anti-platelet activity.

YN370219 XL041 1256918-39-4

XL041 (BMS-852927) is anLXRβ-selective agonist.

YN480583 Aldosterone D8 1261254-31-2

Aldosterone D8 is a deuterium labeled Aldosterone. Aldosterone, produced in the adrenal zona glomerulosa, regulates blood pressure.

YN420085 O-304 1261289-04-6

O-304 (O-304X) is an orally available pan-activator of AMPK activated protein kinase (AMPK). O-304 (O-304X) exhibits a great potential as a novel drug to treat type 2 diabetes (T2D) and associated cardiovascular compl...

YN480901 4-Hydroxyphenyl Carvedilol D... 1261395-96-3

4-Hydroxyphenyl Carvedilol D5 is the deuterium labeled 4-Hydroxyphenyl Carvedilol.

YN360364 GS967 1262618-39-2

GS967 is a potent and selective inhibitor of late INa with anti-arrhythmic actions.

YN480647 TXNIP-IN-1 1268955-50-5

TXNIP-IN-1 isTXNIP-TRX (thioredoxin-interacting protein- thioredoxin) complexinhibitor extracted from patent US20200085800A1, Compound 1. TXNIP-IN-1 can be used in the research of TXNIP-TRX complex associat...

YN450096 Chroman 1 1273579-40-0

Chroman 1 dihydrochloride is a highly potentROCK2inhibitor, with an IC50 of 1nM. Chroman 1 dihydrochloride also shows inhibitory activities againstMRCK, with an IC50 of 150nM.

YN372447 Rosuvastatin D3 Sodium 1279031-70-7

Rosuvastatin D3 Sodium is deuterium labeled Rosuvastatin, which is a competitive inhibitor of HMG-CoA reductase with IC50 of 11nM.

YN320407 BMS-813160 1286279-29-5

BMS-813160 is a potent, well-absorbed dual CCR2 and CCR5 chemokine antagonist. BMS-813160 inhibits inflammatory processes, angiogenesis, tumor cell migration, tumor cell proliferation and invasion.

YN371016 N-Acetyl lysyltyrosylcystein... 1287585-40-3

N-Acetyl lysyltyrosylcysteine amide is a potent, reversible, specific, and non-toxic tripeptide inhibitor ofmyeloperoxidase (MPO). N-Acetyl lysyltyrosylcysteine amide effectively inhibits MPO generation of toxic oxidants in vivo...

YN350176 BIX 02565 1311367-27-7

BIX 02565 is a potent ribosomal S6 kinase 2 (RSK2) inhibitor with IC50 of 1.1nM.

YN320517 Vicagrel 1314081-53-2

Vicagrel, an acetate derivative of Clopidogrel, is aP2Y12platelet inhibitor potentially for the treatment of thrombosis, the substrate of carboxylesterase 2 (CES2). Vicagrel demonstrates a favorable safety profile and excellent an...