Chemical structure
Cat.No.
Product Name
CAS no.
Target
YN320951 Reparixin L-lysine salt 266359-93-7
Reparixin L-lysine salt is an allosteric inhibitor ofchemokine receptor 1/2 (CXCR1/2)activation.
Udenafil is a potent antagonist of human PDE5 with an IC50 of 8.25 nM and a comparable selectivity profile as sildenafil for the other PDEs.
YN320937 Pardoprunox hydrochloride 269718-83-4
Pardoprunox (SLV-308, DU-126891, SME-308) hydrochloride (HCl) is a potent but partial dopamine D2 receptor agonist with pEC50 of 8.0, and a partial agonist in the induction of [35S]GTPγS binding ...
YN320936 Pardoprunox 269718-84-5
Pardoprunox (SLV-308) is a partialdopamine D2 and D3 receptorpartial agonist and aserotonin 5-HT1A receptoragonist, withpEC50s of 8, 9.2, and 6.3, respectively.
YN321301 SB-408124 288150-92-5
SB408124 is a non-peptide antagonist for OX1 receptor with Ki of 57 nM and 27 nM in both whole cell and membrane, respectively, exhibits 50-fold selectivity over OX2 receptor.
YN320540 BX471 hydrochloride 288262-96-4
BX471 hydrochloride (ZK-811752 hydrochloride) is a potent, selective non-peptideCCR1antagonist with Kiof 1nM for human CCR1, and exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4.
YN321065 Treprostinil sodium 289480-64-4
Treprostinil sodium (UT-15, Remodulin, Orenitram, Tyvaso, Trevyent) is a potent agonist of DP1, EP2 and IP receptors with Ki 4.4 nM, 3.6 nM and 32 nM, respectively.
YN321060 Netupitant 290297-26-6
Netupitant is a selective neurokinin 1 (NK1) receptor antagonist with potential antiemetic activity.
YN320947 Avosentan 290815-26-8
Avosentan(Ro 67-0565; SPP-301) is a potent, selective endothelin receptor(ETA receptor) antagonist.
RS102895 is a potentCCR2antagonist, with an IC50 of 360nM, and shows no effect on CCR1.
YN320981 RS 504393 300816-15-3
RS 504393 is a selectiveCCR2chemokine receptor antagonist (IC50 values are 89nM and > 100μM for inhibition of human recombinant CCR2 and CCR1 receptors respectively).
YN321972 Neuropeptide Y(29-64) 303052-45-1
Neuropeptide Y(29-64) is a 36 amino acid peptide, a fragment of Neuropeptide Y.
HT-2157 (SNAP 37889) is a selective, high-affinity, competitive antagonists ofgalanin-3 receptor(Gal3).
AVE 0991 is a nonpeptide and orally activeangiotensin-(1-7) receptoragonist with an IC50 of 21nM.
YN371345 8-Demethyl Ivabradine 304464-97-9
8-Demethyl Ivabradine is a metabolite of Ivabradine. Ivabradine is an orally bioavailable, hyperpolarization-activated, cyclic nucleotide-gated (HCN) channel blocker.
YN481445 Tanaproget 304853-42-7
Tanaproget (NSP-989) is a novel nonsteroidal progesterone receptor agonist which can bind to the PR from various species with a higher relative affinity than reference steroidal progestins.
YN321033 AVE 0991 sodium salt 306288-04-0
AVE 0991 sodium salt is a nonpeptide and orally activeAng-(1-7) receptor Masagonist. AVE 0991 competes for high-affinity binding of [125I]-Ang-(1-7) to bovine aortic endothelial cell membranes with IC50 of 21nM.
YN480030 Sufugolix 308831-61-0
Sufugolix (TAK-013) is a highly potent and orally available luteinizing hormone-releasing hormone (LHRH) receptor antagonist with an IC50 of 0.1nM.
YN320844 Indacaterol 312753-06-3
Indacaterol is an ultra-long-acting β-adrenoceptor agonist with pKi of 7.36 for β1-adrenoceptor and pKi of 5.48 for β2-adrenoceptor.
MK-0557 is a highly selective, orally available neuropeptideY5receptor antagonist with a Ki of 1.6nM.
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