YN320169 NRA-0160 204718-47-8

NRA-0160 is a selectivedopamine D4 receptorantagonist, with aKivalue of 0.48nM and with negligible affinity fordopamine D2 receptor(Ki: >10000nM),D3 receptor(Ki: 39nM), rat5-HT2A receptor(Ki: 180nM) and ratα1 adrenocep...

YN321924 Orexin B, human 205640-91-1

Orexin B, human is an endogenous agonist atOrexinreceptor with Kis of 420 and 36nM for OX1 and OX2, respectively.

YN322019 RS-601 207987-59-5

RS-601 is a novelleukotriene D4 (LTD4)/thromboxane A2 (TxA2)dual receptor antagonist, with antiasthmatic activities.

YN322085 Fiduxosin 208993-54-8

Fiduxosin is a potentα1-adrenoceptorantagonist, with Kiof 0.160nM, 24.9nM, and 0.920nM for α1a-, α1b-, and α1d-adrenoceptors, respectively.

YN321169 Nastorazepide 209219-38-5

Nastorazepide (Z-360) is a selective, orally available, 1,5-benzodiazepine-derivative gastrin/cholecystokinin 2 (CCK-2) receptor antagonist with potential antineoplastic activity. Target：CCK-2 in vitro: Z-360 binds to the gastri...

YN320427 Sitaxsentan sodium 210421-74-2

Sitaxsentan sodium (IPI 1040 sodium; TBC11251 sodium) is an orally active, highly selective antagonist ofendothelin A receptors.

YN484032 Alpha 1(I) Collagen (614-63... 210905-12-7

Alpha 1(I) Collagen (614-639), human is a peptide fragment of alpha-1 type I collagen.

YN481402 Sobetirome 211110-63-3

Sobetirome (GC-1) is a thyroid hormone receptor β (TRβ)-specific agonist which bind selectively toTRβ-1with an EC50 of 0.16μM.

YN320750 ABT-546 212481-66-8

ABT-546 (A-216546) is a potent, highly selective and activeendothelin ETAreceptorantagonist with a Ki of 0.46nM for [125I]endothelin-1 binding to clonedhuman endothelin ETA. ABT-546 is ＞25,000-fold more selective for theE...

YN320310 Cipralisant 213027-19-1

Cipralisant is a potent and selectivehistamine H3 receptorantagonist in vivo, and an agonist in vitro, with a pKi of 9.9 for histamine H3 receptor and a Ki of 0.47nM for rat histamine H3 receptor; Cipralisant has the potential...

YN322063 Neurokinin antagonist 1 214487-45-3

Neurokinin antagonist 1 is aNeurokininantagonist extracted from patent WO1998045262A1.

YN322045 MEN11467 214487-46-4

MEN11467 is a selective and orally- effective peptidomimetictachykinin NK1receptorantagonist.

YN322029 Lusaperidone 214548-46-6

Lusaperidone (R107474) is an α2adrenergic receptorantagonist with Kis of 0.13 and 0.15nM for α2A and α2C, respectively.

YN321055 Degarelix 214766-78-6

Degarelix is a competitive and reversible gonadotropin-releasing hormone receptor (GnRHR) antagonist.

YN320030 FR167344 free base 215258-13-2

FR167344 free base is an orally active, nonpeptidebradykinin receptor B2antagonist. FR167344 free base shows a high affinity binding to the B2 receptor with an IC50 value of 65nM and no binding affinity for the B1 receptor.

YN320158 Bamirastine 215529-47-8

Bamirastine inhibits lig and binding to recombinant human histamine H1receptors (rhH1R) with an IC50 value of 17.3nM.

YN360607 Esomeprazole magnesium trihyd... 217087-09-7

Esomeprazole magnesium trihydrate ((S)-Omeprazole magnesium trihydrate) is a potent and orally activeH+, K+-ATPaseinhibitor. Esomeprazole magnesium trihydrate has the potential for upper intestinal disorders and gastroesophagea...

YN320539 BX471 217645-70-0

BX471 (ZK-811752) is an orally active, potent and selective non-peptideCCR1antagonist with a Ki of 1nM, and exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4.

YN322054 KP496 217799-03-6

KP496 is a selective, dual antagonist forLeukotriene D4 receptor and Thromboxane A2 receptor.

YN320507 Dabuzalgron 219311-44-1

Dabuzalgron (Ro 115-1240) is an orally active and selectiveα-1A adrenergic receptoragonist for the treatment of urinary incontinence. Dabuzalgron protects against Doxorubicin-induced cardiotoxicity by preserving mitochondrial functi...