YN320434 ALB-127158(a) 1173154-32-9

ALB-127158(a) is a potent and selective melanin concentrating hormone 1 (MCH1) receptor antagonist.

YN320707 AM211 1175526-27-8

AM211 is a potent, selective and orally bioavailableprostagl and in D2 (PGD2) receptor type 2 (DP2)antagonist, with IC50s of 4.9nM, 7.8nM, 4.9nM, 10.4nM for human, mouse, guinea pig, and rat DP2, respectively.

YN481389 RAD140 1182367-47-0

RAD140 is a potent, orally bioavailable, nonsteroidal selective androgen receptor modulator with Ki value of 7 nM as well as good selectivity over other steroid hormone nuclear receptors.

YN321608 Cinnarizine D8 1185242-27-6

Cinnarizine D8 is a deuterium labeled Cinnarizine. Cinnarizine is an antihistamine and a calcium channel blocker.

YN320473 ML-109 1186649-91-1

ML-109 is a potent and full thyroid stimulating hormone receptor (TSHR) agonist, with an EC50of 40nM.

YN321171 Omidenepag 1187451-41-7

Omidenepag,a pharmacologically active form of Omidenepag Isopropyl, is a selective, non-prostanoidEP2receptor agonist, with an EC50 of 1.1nM. Omidenepag shows binding affinities (IC50) 10nM for h-EP2.

YN321089 Ralinepag 1187856-49-0

Ralinepag is a potent, orally bioavailable  and  non-prostanoidprostacyclin (IP) receptoragonist, with EC50s of 8.5nM, 530nM  and  850nM for human  and  rat IP receptor  and  human DP1 ...

YN321532 Hydroxyzine D8 1189480-47-4

Hydroxyzine D8 is deuterium labeled Hydroxyzine. Hydroxyzine is ahistamine H1-receptorantagonist.

YN321226 (±)-Methotrimeprazine (D6) 1189805-51-3

(±)-Methotrimeprazine (D6) is the deuterium labeled Methotrimeprazine, which is a D3 dopamine and Histamine H1 receptor antagonist.

YN320151 GSK1059865 1191044-58-2

GSK1059865 is a potentorexin 1 receptorantagonist.

YN321252 Burixafor hydrobromide 1191450-19-7

Burixafor hydrobromide (TG-0054 hydrobromide) is an orally bioavailable and potent antagonist ofCXCR4 and a well water soluble anti-angiogenic drug that is of potential value in treating choroid neovascularization. Burixafor hydr...

YN320749 ADRA1D receptor agonist 1 1191908-14-1

ADRA1D receptor agonist 1 (compound (R)-9S) is a potent, selective and orally activeα1Dadrenoceptorantagonist, with a Ki of 1.6nM.

YN320437 AZD7594 1196509-60-0

AZD7594 is a potent selective nonsteroidalglucocorticoid receptormodulator, with an IC50 of 0.9nM.

YN360605 Esomeprazole magnesium salt 1198768-91-0

Esomeprazole magnesium salt ((S)-Omeprazole magnesium salt) is a potent and orally active proton pump inhibitor and reduces acid secretion through inhibition of theH+, K+-ATPasein gastric parietal cells. Esomeprazole magnesium ...

YN321013 INT-777 1199796-29-6

INT-777 is a potentTGR5agonist with an EC50 of 0.82μM.

YN320545 BI-167107 1202235-68-4

BI-167107 is a high affinity, full agonist that binds to the β2 adrenergic receptor (β2AR) with a dissociation constantKdof 84 pM.

YN320993 SRT3109 1204707-71-0

SRT3109 is an antagonist ofCXCR2, with apIC50 of 8.2, and used in the research of chemokine mediated diseases.

YN320682 SRT3190 1204707-73-2

SRT3190 is an antagonist ofCXCR2, used in the research of chemokine mediated diseases.

YN321257 MK-1064 1207253-08-4

MK1064 is a selective orexin 2 receptor antagonist (2-SORA) with an IC50 of 18 nM.

YN320656 KAG-308 1215192-68-9

KAG-308 is a potent selective and orally active agonist ofEP4 receptor(a prostagl and in E2 receptor subtype), suppresses colitis and promotes histological mucosal healing, potently inhibits TNF-α production. KAG-308 shows ...