YN321162 Atosiban acetate 914453-95-5

Atosiban acetate (RW22164 acetate;RWJ22164 acetate) is a nonapeptide competitivevasopressin/oxytocin receptorantagonist, and is a desamino-oxytocin analogue. Atosiban is the main tocolytic agent and has the potential for spontane...

YN320346 MF498 915191-42-3

MF498 is a novel and selective E prostanoid receptor 4 (EP4 receptor) antagonist, displayed strong binding affinity for the EP4 receptor with Ki of 0.7nM.

YN320392 TCS 1102 916141-36-1

TCS 1102 is a potent, dual orexin receptor antagonist (Ki values are 0.2 and 3nM for OX2 and OX1 receptors respectively).

YN480249 LGD-3303 917891-35-1

LGD-3303 is a selective and rogen receptor modulator (SARM).

YN321253 Setmelanotide 920014-72-8

Setmelanotide (RM-493, BIM-22493, CAM 4072) is a cyclic peptide full agonist of melanocortin-4 receptor (MC4R) with an EC50 of 0.27 nM and a Ki of 2.1 nM.

YN320672 RG7713 920022-47-5

RG7713 (RO5028442) is a highly potent  and  selectiveBrain-Penetrant Vasopressin 1a(V1a) receptor antagonist with Kis of 1nM (hV1a)  and  39nM (mV1a).

YN480749 Resmetirom 920509-32-6

Resmetirom is a liver-directed, orally active, selective thyroid hormone receptor β(THR-β) agonist with an EC50 of 0.21 μM,shows 28-fold selective for THR-β over THR-α in a functional assay.

YN321088 Centanafadine hydrochloride 923981-14-0

Centanafadine (hydrochloride) is dualnorepinephrine (NE)/dopamine (DA)transporter inhibitor, also inhibits serotonin transporter, with IC50s of 6nM, 38nM and 83nM for human NE, DA and serotonin transporter , respectively.

YN320520 AZ084 929300-19-6

AZ084 is a potent, selective, allosteric and oral activeCCR8antagonist, with a Ki of 0.9nM. Has potential to treat asthma.

YN321090 Asapiprant 932372-01-5

Asapiprant is a potent and selectiveDP1receptorantagonist with a Ki of 0.44nM.

YN270375 Azoramide 932986-18-0

Azoramide is a small-molecule modulator of the unfolded protein response (UPR). It improves ER protein-folding ability and activates ER chaperone capacity to protect cells against ER stress.

YN480442 PF-02413873 936345-35-6

PF-02413873 (PF-2413873) is a potent selective, fully competitive and orally active nonsteroidalprogesterone receptor (PR)antagonist, with a Ki of 2.6nM. PF-02413873 can block progesterone binding and PR nuclear translocatio...

YN321181 LCZ696 936623-90-4

Sacubitril/valsartan (LCZ696), consisting of valsartan and sacubitril in 1:1 molar ratio, is an orally bioavailable, dual-acting angiotensin receptor-neprilysin inhibitor (ARNi) for hypertension and heart failure. Phase 3.

YN320869 Pavinetant 941690-55-7

Pavinetant (MLE-4901) is aneurokinin-3 receptor(NK3R) antagonist.

YN320448 GSK726701A 945721-87-9

GSK726701A is a novelprostagl and in E2 receptor 4 (EP4)partial agonist with apEC50of 7.4.

YN320557 LMD-009 950195-51-4

LMD-009 is a selectiveCCR8nonpeptide agonist. LMD-009 mediates chemotaxis, inositol phosphate accumulation, and calcium release in high potencies with EC50s from 11 to 87nM.

YN320966 Timapiprant sodium 950688-14-9

Timapiprant sodium (OC000459 sodium) is a potent, selective, and orally active D prostanoid receptor 2 (DP2, also known asCRTH2) antagonist. Timapiprant sodium (OC000459 sodium) potently displaces [3H] PGD2 from human rec...

YN321245 Danirixin 954126-98-8

Danirixin (GSK1325756) is a small molecule, non-peptide, high affinity (IC50 for CXCL8 binding = 12.5 nM), selective, and reversible CXCR2 antagonist.

YN321066 UNBS5162 956590-23-1

UNBS5162 is a pan-antagonist ofCXCL chemokineexpression, with anti-tumor activity.

YN320756 Betamethasone hydrochloride 956901-32-9

Betamethasone hydrochloride is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive activities. Betamethasone hydrochloride accelerates fetal lung maturation and induces gene expression and apoptosis.