YN370244 Simeprevir 923604-59-5

Simeprevir is a competitive, reversible, macrocyclic, noncovalent hepatitis C virus (HCV) NS3/4A protease inhibitor that acts directly against the hepatitis C virus. It has a medium inhibitory concentration (IC50) <13 nM for al...

YN250663 RRx-001 925206-65-1

RRx-001 is a novel epigenetic modulator with potential radiosensitizing activity. It inhibits glucose 6-phosphate dehydrogenase(G6PD) in human tumor cells, binds hemoglobin and drives RBC-mediated redox reactions under hypoxia.

YN250814 Triazavirin 928659-17-0

Triazavirin is a novel antiviral drug, a nucleoside analogue of nucleic acid that inhibits the synthesis of viral RNA and DNA and replication of genomic fragments. Triazavirin is active against influenza and a number of other viruse...

YN250781 E1210 936339-60-5

E1210 is a first-in-class, broad-spectrum and orally active antifungal. E1210 has a mechanism of action-inhibition of fungal glycosylphosphatidylinositol (GPI) biosynthesis.

YN251860 IDR-1 940291-10-1

IDR-1 is an antimicrobial peptide that is active againstGram-positive and Gram-negative bacteria. IDR-1 counters infection by selective modulation of innate immunity without obvious toxicities. IDR-1 has anti-inflammatory and a...

YN250086 Mericitabine 940908-79-2

Mericitabine (RG 7128; R-7128) is a nucleoside inhibitor of theHCV NS5B polymerasethat acts as an RNA chain terminator and prevents elongation of RNA transcripts during replication.

YN250179 Inarigivir soproxil 942123-43-5

Inarigivir soproxil is an agonist of innate immunity and shows potent antiviral activity against resistant hepatitis C virus(HCV)variants, with EC50s of 2.2 and 1.0μM for HCV 1a/1b in cells of genotype 1 HCV replicon syst...

YN250022 Isavuconazonium sulfate 946075-13-4

Isavuconazonium sulfate (BAL8557-002), the prodrug of the active triazole Isavuconazole, is an orally active antifungal agent. Isavuconazonium sulfate is used for invasive aspergillosis and mucormycosis.

YN483470 Ascr#3 946524-26-1

Ascr#3 is an ascaroside isolated fromCaenorhabditis elegans, acts a potent male attractant, and also promotes dauer formation combined with ascr#2 at low concentration.

YN250459 Cefpodoxime proxetil impurity... 947692-14-0

Cefpodoxime proxetil impurity B is an impurity of Cefpodoxime proxetil (HY-N7101). Cefpodoxime Proxetil is a first oral and broad spectrum antibiotic that belongs to the third generation of cephalosporin.

YN251780 Kipukasin D 948574-00-3

Kipukasin D is an natural nucleoside derived fromAspergillus versicolorwith antibacterial activity.

YN250357 TTP-8307 950225-08-8

TTP-8307 is a potent inhibitor of the replication of severalrhino- and enteroviruses. TTP-8307 inhibits coxsackievirus B3 (CVB3; EC50=1.2μM) and poliovirus by interfering with the synthesis ofviral RNA. TTP-8307 exer...

YN250073 KKL-10 952849-76-2

KKL-10 is an inhibitor of ribosome rescue that exhibits exceptional broad-spectrum antimicrobial activity against bacteria.

YN250178 Valnivudine 956483-02-6

Valnivudine (FV-100 free base), a prodrug of CF-1743, is an orally active anti-herpes zoster (HZ) nucleoside analogue. CF-1743, a bicyclic nucleoside analog (BCNA), has highly specific antiviral activity against varicella-zoste...

YN250499 BTZ043 Racemate 957217-65-1

BTZ043 racemate is a decaprenylphosphoryl-β-D-ribose 2'-epimerase (DprE1) inhibitor acting as a new antimycobacterial agent that kill Mycobacterium tuberculosis.

YN250343 Beclabuvir 958002-33-0

Beclabuvir is an allosteric inhibitor that binds to thumb site 1 of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase, and inhibits recombinant NS5B proteins from HCV genotypes 1, 3, 4, and 5 with IC50 ...

YN483819 Hexa-D-arginine TFA 958204-56-3

Hexa-D-arginine TFA (Furin Inhibitor II TFA) is a stablefurininhibitor with Ki values 106nM, 580nM and 13.2μM forfurin, PACE4 and prohormone convertase-1 (PC1), respectively. Hexa-D-arginine TFA blocksPseudo...

YN370269 SID 26681509 958772-66-2

SID 26681509 is a potent, reversible, competitive, and selective inhibitor ofhuman cathepsin Lwith an IC50 of 56nM. SID 26681509 inhibits in vitro propagation of malaria parasitePlasmodium falciparum and inhibitsLeishmania ma...

YN250454 CBS1117 959245-08-0

CBS1117 is a virus entry inhibitor with an IC50 of 70nM for influenza A viruses, A/Puerto Rico/8/34 (H1N1). CBS1117 interferes with the hemagglutinin (HA)-mediated fusion process.

YN250186 PF 03709270 1000296-70-7

PF 03709270 is an orally available ester prodrug form of sulopenem, with broad-spectrum antibacterial activity against most gram-positive and gram-negative bacteria.