YN250692 Peramivir trihydrate 1041434-82-5

Peramivir trihydrate (RWJ-270201 trihydrate;BCX-1812 trihydrate) is a highly potent, selective and orally active influenza virusneuraminidase (NA)inhibitor, with IC50 values ranging from 0.9 to 4.3nM for nine NA subtypes.

YN250432 NITD008 1044589-82-3

NITD008 is a potent and selectiveflaviviruseinhibitor which can inhibitDengue Virus Type 2 (DENV-2)with an EC50 of 0.64μM.

YN372320 Cabotegravir 1051375-10-0

Cabotegravir (GSK744, GSK1265744) is a long-acting HIV integrase inhibitor against a broad range of HIV subtypes, and inhibits the HIV-1 integrase catalyzed strand transfer reaction with IC50 of 3.0 nM. Phase 2.

YN371361 Dolutegravir 1051375-16-6

Dolutegravir (GSK1349572) is a two-metal-binding HIV integrase inhibitor with IC50 of 2.7 nM in a cell-free assay, modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H.

YN371362 Dolutegravir sodium 1051375-19-9

Dolutegravir sodium is a HIV integrase inhibitor with IC50 of 2.7 nM.

YN250588 MAC13243 1071638-38-4

MAC13243, an antibacterial agent, is an inhibitor of bacterial lipoprotein targeting chaperone,LolA. MAC13243 is an antibacterial agent with Gram-negative selectivity.

YN251729 1,3,5-Tricaffeoylquinic acid 1073897-80-9

1,3,5-Tricaffeoylquinic acid is a tricaffeoylquinic acid derivative isolated fromH. populifoliumwith anti-HIV effect.

YN250678 Gepotidacin 1075236-89-3

Gepotidacin (GSK2140944) is a novel triazaacenaphthylene bacterial type IItopoisomeraseinhibitor.

YN483471 Ascr#5 1086696-26-5

Ascr#5 is a highly conserved ascaroside isolated fromCaenorhabditis elegans.

YN251636 ent-11β-Hydroxyatis-16-ene-3... 1092103-22-4

ent-11β-Hydroxyatis-16-ene-3,14-dione (compound 11) is a diterpenoid from the fresh roots ofEuphorbia jolkinii. ent-11β-Hydroxyatis-16-ene-3,14-dione hasanti-RSVactivity.

YN250173 Morphothiadin 1092970-12-1

Morphothiadin is a potent inhibitor on the replication of both wild-type and adefovir-resistantHBVwith an IC50 of 12nM.

YN250746 PLpro inhibitor 1093070-14-4

PLpro inhibitor (compound 6) is a potent papain-like protease (PLpro)/deubiquitinase (DUBs) inhibitor with IC50 of 2.6 μM and EC50 of 13.1 μM that blocks SARS virus replication.

YN250263 GRL0617 1093070-16-6

GRL0617 is a potent, selective and competitive noncovalent inhibitor of severe acute respiratory syndrome (SARS-CoV) papain-like protease (PLPro)/deubiquitinase with IC50 of 0.6 μM and Ki of 0.49 μM. GRL0617 inhibits S...

YN250468 Oseltamivir D3 1093851-61-6

Oseltamivir D3 is a deuterium labeled Oseltamivir. Oseltamivir is aninfluenza virus neuraminidaseinhibitor (NAI). Oseltamivir inhibits influenza A/H3N2, A/H1N2, A/H1N1, and B viruses with meanIC50s of 0.67, 0.9, 1.34 ...

YN360600 Afoxolaner 1093861-60-9

Afoxolaner is an orally active isoxazoline insecticide/acaricide againstIxodes scapularisin dogs. Afoxolaner acts on the insectγ-aminobutyric acid receptor (GABA) and glutamate receptors, inhibiting GABA & glutamate-regulated up...

YN372664 SPK-601 1096687-52-3

SPK-601 (LMV-601) is an inhibitor of thephosphatidylcholine-specific phospholipase C (PC-PLC). SPK-601 also can be used as an antimicrobial agent.

YN250823 Contezolid 1112968-42-9

Contezolid (MRX-I), a new and oraly active oxazolidinone, is an antibiotic in study for complicated skin and soft tissue infections (cSSTI) caused by resistant Gram-positive bacteria. Contezolid (MRX-I) markedly reduces p...

YN250792 FIT-039 1113044-49-7

FIT-039 is a selective, ATP-competitive and orally active CDK9 inhibitor with an IC50 of 5.8μM forCKD9/cyclin T1. FIT-039 does not inhibit other CDKs and other kinases. FIT-039 inhibits replication ofHSV-1(I...

YN250098 Linezolid D3 1127120-38-0

Linezolid D3 is a deuterium labeled Linezolid (PNU-100766). Linezolid is a synthetic antibiotic that acts by inhibiting the initiation of bacterial protein synthesis.

YN250579 Dasabuvir 1132935-63-7

Dasabuvir(ABT-333) is a non-nucleoside inhibitor of NS5B viral RNA-dependent RNA polymerase that inhibits recombinant NS5B polymerases derived from HCV genotype 1a and 1b clinical isolates with IC50 values between 2.2 a...