YN250063 ABT-072 1132936-00-5

ABT-072 is a nonnucleosideNS5B polymeraseinhibitor and a c and idate drug evaluated for treatment of hepatitis C virus.

YN250704 Posaconazole-D4 1133712-26-1

Posaconazole-D4 is a deuterium-labeled form of Posaconazole. Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity.

YN250332 Q-VD-OPh 1135695-98-5

Q-VD-Oph is a potent pan-caspase inhibitor with IC50 ranged from 25 to 400 nM for caspases 1,3,8, and 9.

YN250914 Tigecycline mesylate 1135871-27-0

Tigecycline mesylate (GAR-936 mesylate) is a broad-spectrum glycylcycline antibiotic. The mean inhibitory concentration (MIC) of Tigecycline forE. coli(MG1655 strain) is approximately 125 ng/mL. MIC50 and MIC90are 1 and...

YN250032 Golgicide A 1139889-93-2

Golgicide A is a potent and rapidly reversible GBF1 inhibitor.

YN250853 Etravirine D4 1142095-93-9

Etravirine D4 (TMC-125 D4) is the deuterium labeled Etravirine. Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV.

YN250349 FGI-106 tetrahydrochloride 1149348-10-6

FGI-106 tetrahydrochloride is a potent and broad-spectrum inhibitor with inhibitory activity against multiple viruses. FGI-106 tetrahydrochloride is active againstEbola,Rift Valley and Dengue Fever viruseswith EC50s of 100nM...

YN372490 BI 224436 1155419-89-8

BI 224436 is a novelHIV-1noncatalytic site integrase inhibitor withEC50values of less than 15nM against different HIV-1 laboratory strains.

YN330067 Gardiquimod diTFA 1159840-61-5

Gardiquimod diTFA, an imidazoquinoline analog, is aTLR7/8agonist. Gardiquimod diTFA could inhibit HIV-1 infection of macrophages and activated peripheral blood mononuclear cells (PBMCs). Gardiquimod diTFA specificall...

YN483925 TAT 2-4 1159916-66-1

TAT 2-4 is a peptide derived from HIV-1 transactivator of transcription (Tat) protein.

YN250497 BTZ043 1161233-85-7

BTZ043 is an inhibitor ofdecaprenyl-phosphoribose-epimerase (DprE1), with MICs of of 2.3nM and 9.2nM forM. tuberculosis H37Rv and Mycobacterium smegmatis, respectively.

YN483469 Ascr#8 1172120-40-9

Ascr#8 is an dauer-inducing ascaroside isolated fromCaenorhabditis elegans, synergizes with ascr#2 and ascr#3, and strongly enhances male attraction.

YN250679 Relebactam 1174018-99-5

Relebactam (MK-7655) is a potent inhibitor against KPC-2, class A and class C (AmpC) β-lactamases.

YN484134 Competence-Stimulating Pept... 1174553-84-4

Competence-Stimulating Peptide-2 (CSP-2) is a quorum sensing signal peptide produced byStreptococcus pneumoniae. ComD2 is a compatible receptor of Competence-Stimulating Peptide-2 (CSP-2) with an EC50 value of 50.7nM.

YN250643 Braco-19 trihydrochloride 1177798-88-7

Braco-19 trihydrochloride is a potenttelomerase/telomereinhibitor, preventing the capping and catalytic action of telomerase. Braco-19 acts as G-quadruplex (GQ) binding lig and , stabilizing G-quadruplexes formation at the 3V telom...

YN251136 Lumefantrine D18 1185240-53-2

Lumefantrine D18 is the deuterium labeled Lumefantrine, which is an antimalarial drug.

YN250949 Sulfapyridine D4 1189863-86-2

Sulfapyridine D4 a deuterium labeled Sulfapyridine. Sulfapyridine is a sulfonamide antibacterial.

YN250840 M2 ion channel blocker 1190215-03-2

M2 ion channel blocker is capable of inhibiting and blocking the activity of M2 ion channel;Antiviral agent.

YN250618 Sofosbuvir 1190307-88-0

Sofosbuvir (PSI-7977, GS-7977) is a HCV NS5B polymerase inhibitor for the treatment of chronic hepatitis C virus (HCV) infection.

YN250093 GS-441524 1191237-69-0

GS-441524, a molecular precursor to a pharmacologically active nucleoside triphosphate molecule, is a potent inhibitor of feline infectious peritonitis virus (FIPV) with EC50 of 0.78 μM.