YN250575 Tenofovir maleate 1236287-04-9

Tenofovir Disoproxil Fumarate is anucleotide reverse transcriptase inhibitorto treat HIV and chronic Hepatitis B.

YN250469 Oseltamivir acid D3 1242184-43-5

Oseltamivir acid D3 (GS 4071 D3) is a deuterium labeled Oseltamivir acid. Oseltamivir acid, the active metabolite of Oseltamivir phosphate, is an orally bioavailable, potent and selective inhibitor ofinfluenza virus neuraminidase ...

YN250967 Praziquantel D11 1246343-36-1

Praziquantel D11 is the deuterium labeled Praziquantel, which is an anthelmintic.

YN410089 Curcumin D6 1246833-26-0

Curcumin D6 (Diferuloylmethane D6) is a deuterium labeled Curcumin (Turmeric yellow). Curcumin (Turmeric yellow) is a natural phenolic compound with diverse pharmacologic effects including anti-inflammatory, antioxidant, antiprolife...

YN350204 ITX5061 1252679-52-9

ITX5061 is a type II inhibitor ofp38 MAPK and also an antagonist ofscavenger receptor B1(SR-B1).

YN250627 UNC0638 1255580-76-7

UNC0638 is a potent, selective and cell-penetrant chemical probe for G9a and GLP with IC50 of <15 nM and 19 nM, respectively, shows selectivity over a wide range of epigenetic and non-epigenetic targets.

YN250646 Ledipasvir 1256388-51-8

Ledipasvir (GS5885) is a HCV NS5A polymerase inhibitor, used for the treatment of hepatitis C virus infection.

YN250626 PSI-6206 13CD3 1256490-42-2

PSI-6206 13CD3 is the deuterium labeled PSI-6206. PSI-6206 is the deaminated derivative of PSI-6130, which is a potent and selective inhibitor of HCV NS5B polymerase. PSI-6206 low potently inhibitsHCV repliconwit...

YN250358 TBA-354 1257426-19-9

TBA-354 is a potent anti-tuberculosis compound; maintains activity against Mycobacterium tuberculosis H37Rv isogenic monoresistant strains.

YN251075 Amikacin hydrate 1257517-67-1

Amikacin is an aminoglycoside antibiotic used to treat different types of bacterial infections.

YN250578 Ombitasvir 1258226-87-7

Ombitasvir (ABT-267) is an inhibitor of the HCV non-structural protein 5A with antiviral activity.

YN250046 ABX464 1258453-75-6

ABX464 is a novel anti-HIV molecule that inhibits HIV-1 replication in stimulated peripheral blood mononuclear cells (PBMCs) from 5 different donors with IC50 ranging between 0.1 μM and 0.5 μM.

YN330148 Sparstolonin B 1259330-61-4

Sparstolonin B acts as a selectiveTLR2 and TLR4antagonist and selectively blocks TLR2- and TLR4-mediated inflammatory signaling. Sparstolonin B has anti-HIV and anticancer activities.

YN290395 CDK9-IN-2 1263369-28-3

CDK9-IN-2 is a special cyclin-dependent kinase 9 (CDK9) inhibitor, extracted from patent WO/2012131594A1, compound CDKI(8), has an IC50 of 5nM and 7nM in H929 multiple myeloma(MM) cell line (72 hours) and A2058 sk...

YN250082 Antifungal agent 1 1265166-14-0

Antifungal agent 1 is a potentantifungalagent.

YN250822 Acoziborole 1266084-51-8

Acoziborole (SCYX-7158) is an effective, safe and orally active antiprotozoal agent for the research of human african trypanosomiasis (HAT). In theT. b. bruceiS427 strain, theMICvalue for SCYX-7158 is 0.6 µg/mL.

YN250403 AN3661 1268335-33-6

AN3661, a potent antimalarial lead compound, targets aPlasmodium falciparumcleavage and polyadenylation specificity factor homologue subunit 3(PfCPSF3). AN3661 inhibitsPlasmodium falciparumlaboratory-adapted strains (mean IC5...

YN250779 MUT056399 1269055-85-7

MUT056399 (Fab-001) is a highly potent inhibitor of the FabI enzymeof both S. aureus and E. coli with 50% inhibitory concentrationIC50s of 12nM and 58nM, respectively.

YN250200 3'-Azido-3'-deoxy-5-methylcyt... 1282040-14-5

3'-Azido-3'-deoxy-5-methylcytidine (CS-92) is a potent xenotropic murine leukemia-related retrovirus (XMRV) inhibitor with aCC50of 43.5μM in MCF-7 cells. 3'-Azido-3'-deoxy-5-methylcytidine also inhibitsHIV-1 reverse transc...

YN370015 DSM265 1282041-94-4

DSM265 is a long-duration inhibitor of P. falciparumdihydroorotate dehydrogenase (PfDHODH) with an IC50 of 8.9nM. DSM265 can also inhibit the growth of Pf3D7 parasites with an EC50 of 4.3nM.